Evidence map›Paper›PMID 40949376›Full record

ArticleWorld journal of gastrointestinal surgery2025

Preoperative performance status was associated with postoperative fatal complications in elderly patients with refractory ulcerative colitis.

Yuki Horio, Motoi Uchino, Yusuke Tomoo, Kazunori Nomura, Kentaro Nagano, Kurando Kusunoki, Ryuichi Kuwahara, Kei Kimura, Toshiyuki Sato, Kozo Kataoka and 4 more

Abstract read
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In one paragraph

Article in World journal of gastrointestinal surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Yuki HorioDepartment of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya 663-8501, Hyogo, Japan. yu-horio@hyo-med.ac.jp.
Motoi UchinoDepartment of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya 663-8501, Hyogo, Japan.
Yusuke TomooDepartment of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya 663-8501, Hyogo, Japan.
Kazunori NomuraDepartment of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya 663-8501, Hyogo, Japan.
Kentaro NaganoDepartment of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya 663-8501, Hyogo, Japan.
Kurando KusunokiDepartment of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya 663-8501, Hyogo, Japan.
Ryuichi KuwaharaDepartment of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya 663-8501, Hyogo, Japan.
Kei KimuraDepartment of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya 663-8501, Hyogo, Japan.
Toshiyuki SatoDepartment of Gastroenterology, Hyogo Medical University, Nishinomiya 663-8501, Hyogo, Japan.
Kozo KataokaDepartment of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya 663-8501, Hyogo, Japan.
Masataka IgetaDepartment of Biostatistics, Hyogo Medical University, Nishinomiya 663-8501, Hyogo, Japan.
Shinichiro ShinzakiDepartment of Gastroenterology, Hyogo Medical University, Nishinomiya 663-8501, Hyogo, Japan.
Masataka IkedaDepartment of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya 663-8501, Hyogo, Japan.
Hiroki IkeuchiDepartment of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya 663-8501, Hyogo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundElderly patients with refractory ulcerative colitis (UC) have a poor prognosis, and timely surgical intervention should not be delayed. However, with the advent of biologics, therapy has become more complex, and there are no clear criteria for the timing of surgical conversion.

aimTo investigate the risk factors for postoperative complications in elderly patients with UC.

methodsElderly patients (≥ 60 years old) with refractory UC who underwent colectomy at Hyogo Medical University between April 2012 and March 2024 were included in this study. Fatal complications included life-threatening complications requiring intensive care unit management and death. The primary outcome was defined by possible risk factors for fatal complications in older patients with refractory UC.

resultsA total of 191 elderly patients with UC were analyzed in this series. The rate of fatal complications was 18/191 (9.4%), and the most common complication was pneumonia due to disuse syndrome. Body mass index (BMI) < 17 kg/m

conclusionAmong the elderly patients with refractory UC, the risk factors for fatal complications were low BMI and ECOG-PS score. Prompt surgical intervention is recommended before the patient loses weight or has difficulty walking. These factors may allow for early surgical decision-making before patients become debilitated.

Indexed as

Body mass indexEastern Cooperative Oncology Group performance statusElderlyPostoperative complicationSurgeryUlcerative colitis

Identifiers

PMID40949376
PMCPMC12427077

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