ReviewInternational journal of general medicine2025
Pathogenesis of HIV-Associated Metabolic Syndrome and Clinical Management Recommendations.
Review in International journal of general medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Suppressor of cytokine signaling (SOCS) proteins in human retroviral infections.Molecular biology reports · 2026Review
- Article
- Chronic Infections and Diabetes in Africa: A Narrative Review of Pathogen-Associated Metabolic Risk.Cureus · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The phenomenon of metabolic syndrome in patients with HIV infection has attracted increasing attention. HIV infection increases the risk of metabolic complications, including cardiovascular diseases and diabetes. Meanwhile, the potential metabolic side effects of antiretroviral therapy in HIV patients have emerged as a new clinical challenge. This study delineates the potential mechanisms underlying HIV-associated metabolic syndrome, encompassing inflammation and immune activation, glucose and lipid metabolism disorders, mitochondrial and vascular endothelial abnormalities, gut microbiota dysbiosis, epigenetic alterations, and the application of certain antiretroviral drugs. These mechanisms interact and exacerbate each other, with inflammation and immune activation playing a pivotal role. This study also discusses the potential associations between HIV infection and various metabolic diseases, and consolidates clinical management recommendations for HIV-associated metabolic syndrome, including diet, exercise, and lipid, glucose, and blood pressure management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.