Preparing for ICD-11 transition: lessons from case studies in Argentina and Mexico.

Objectives: To explore the early stages of the International Classification of Diseases 11th Revision (ICD-11) implementation in Argentina and Mexico, focusing on mortality coding, to identify essential elements and key considerations for successful adoption. Methods: Qualitative analysis was conducted using case studies from Argentina and Mexico. Data were collected through interviews, workshops, and document analysis to uncover opportunities, challenges, and strategic decisions in ICD-11 implementation. Results: Key findings highlight the critical role of comprehensive system assessments, strategic partnerships, financial planning, technological readiness, targeted training initiatives, and structured evaluation mechanisms. Both countries emphasized the importance of tailored strategies aligned with their unique contexts and highlighted the need for collaboration across sectors and the establishment of national task forces. Challenges included navigating the complexities of integrating ICD-11 within existing systems and enhancing interoperability through accelerated development of tools and establishment of expert networks. Conclusions: Tailored strategies are essential for integrating ICD-11 into national health information systems. Greater collaboration, establishment of national task forces, and clear monitoring frameworks are crucial for successful implementation. Guided by digital health and health informatics expertise, countries can overcome challenges and align with broader health care objectives, thereby ultimately enhancing global health outcomes through effective ICD-11 adoption. By learning from early adopters such as Argentina and Mexico, other countries can better prepare for their own transitions to ICD-11.