Evidence map›Paper›PMID 40948976›Full record

ArticleFrontiers in bioengineering and biotechnology2025

Drug delivery system based on an antibacterial layer-by-layer coating on urinary catheters: an experimental and simulation approach.

Ruth Pulido, Nelson Naveas, Francisco Javier Fernández-Alonso, Miguel Manso-Silván, Leonardo Soriano, Carlos Torres-Ulloa, Karel Mena-Ulecia, Gonzalo Recio-Sánchez, Juan Paulo Garcia-Sandoval, Jacobo Hernández-Montelongo

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ruth PulidoDepartamento de Química, Universidad de Antofagasta, Antofagasta, Chile.
Nelson NaveasDepartamento de Física Aplicada, Universidad Autónoma de Madrid, Campus de Cantoblanco, Madrid, Spain.
Francisco Javier Fernández-AlonsoDepartamento de Física Aplicada, Universidad Autónoma de Madrid, Campus de Cantoblanco, Madrid, Spain.
Miguel Manso-SilvánDepartamento de Física Aplicada, Universidad Autónoma de Madrid, Campus de Cantoblanco, Madrid, Spain.
Leonardo SorianoDepartamento de Física Aplicada, Universidad Autónoma de Madrid, Campus de Cantoblanco, Madrid, Spain.
Carlos Torres-UlloaDepartmento de Ciencias Matemáticas y Físicas, Universidad Católica de Temuco, Temuco, Chile.
Karel Mena-UleciaDepartmento de Ciencias Biológicas y Químicas, Universidad Católica de Temuco, Temuco, Chile.
Gonzalo Recio-SánchezFacultad de Ingeniería, Arquitectura y Diseño, Universidad San Sebastián, Concepción, Chile.
Juan Paulo Garcia-SandovalDepartmento de Ingeniería Química, Universidad de Guadalajara, Guadalajara, Mexico.
Jacobo Hernández-MontelongoDepartmento de Ciencias Matemáticas y Físicas, Universidad Católica de Temuco, Temuco, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urinary catheters (UCs) are critical in biomedical applications, but prolonged use increases the risk of catheter-associated urinary tract infections (CAUTIs), a leading cause of healthcare-associated infections (HAIs). The present study presents a dual strategy to create an antibacterial surface on commercial Foley silicone UCs by combining a contact-killing effect with the controlled release of antimicrobial compounds. We designed a drug delivery system using a layer-by-layer (LbL) antibacterial coating of carboxymethylcellulose (CMC) and chitosan-silver (CHI-Ag) complexes, with ciprofloxacin (CFX) as the model drug. The resulting LbL coating, about 1

Indexed as

antibacterial coatingdrug deliverylayer-by-layer (LbL)mathematical modelmolecular dynamicsurinary catheters

Identifiers

PMID40948976
PMCPMC12426174

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.