Evidence map›Paper›PMID 40948933›Full record

ArticleVeterinary record open2025

Seroprevalence study of paratuberculosis: Johne's disease, a neglected infection in dairy herds in Apulia (southern Italy).

Michela Galgano, Davide Messina, Francesco D'Amico, Alessio Sposato, Elisabetta Razzuoli, Daniela Mrenoshki, Carmelinda Trisolini, Giuseppe Caldarola, Matteo Beverelli, Donato Ridolfi and 6 more

Abstract read
In one paragraph

Article in Veterinary record open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Michela GalganoStruttura complessa territoriale di Putignano (BA) Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata Putignano (BA) Italy.
Davide MessinaDivision of Veterinary Clinical Science School of Veterinary Medicine and Science Faculty of Medicine and Health Sciences University of Nottingham Loughborough UK.ORCID https://orcid.org/0000-0003-3813-5501
Francesco D'AmicoS.S. Genova e Portualità Marittima Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta Genova Italy.
Alessio SposatoStruttura complessa territoriale di Putignano (BA) Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata Putignano (BA) Italy.
Elisabetta RazzuoliS.S. Genova e Portualità Marittima Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta Genova Italy.
Daniela MrenoshkiDepartment of Veterinary Medicine University of Bari Valenzano Italy.
Carmelinda TrisoliniStruttura complessa territoriale di Putignano (BA) Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata Putignano (BA) Italy.
Giuseppe CaldarolaStruttura complessa territoriale di Putignano (BA) Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata Putignano (BA) Italy.
Matteo BeverelliStruttura complessa territoriale di Putignano (BA) Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata Putignano (BA) Italy.
Donato RidolfiStruttura complessa territoriale di Putignano (BA) Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata Putignano (BA) Italy.
Carmela BulzacchelliStruttura complessa territoriale di Putignano (BA) Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata Putignano (BA) Italy.
Anna GiannicoStruttura complessa territoriale di Putignano (BA) Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata Putignano (BA) Italy.
Antonio ParisiStruttura complessa territoriale di Putignano (BA) Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata Putignano (BA) Italy.
Alessandra TateoDipartimento di Medicina di Precisione e Rigenerativa e Area Jonica (DiMePRe-J) University of Bary Bari Italy.
Annamaria PratelliDepartment of Veterinary Medicine University of Bari Valenzano Italy.
Domenico BuonavogliaDepartment of Veterinary Medicine University of Bari Valenzano Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Paratuberculosis (PTB) is a disease caused by Objectives: The objectives were to determine the apparent (AP) and true (TP) prevalences of MAP infection, at the inter-herd (between-herd, BH) and intra-herd (within-herd, WH) levels, and the odds ratio (OR) to assess the probability of both cattle and herds testing positive in the provinces of Apulia, in southern Italy. Methods: A total of 6056 serum samples collected from 341 different dairy farms were analysed by ELISA. The number of farms and cattle required, BH and WH prevalence estimates, ORs, 95% confidence interval values (CIs) and Results: A low overall TP was estimated at both the BH level (17.14%) and WH level (0.82%). Statistically significant differences in OR ( Conclusions: Our results provide the first data on the prevalence of PTB in Apulian dairy herds, according to the following criteria: (i) use of a multi-step sample size calculation procedure considering the test's imperfection; (ii) selection of larger sample sizes of both herds; (iii) inclusion of herds and cattle from the Apulia region only recruited randomly; and (iv) analysis of the test results using non-Bayesian approaches.

Indexed as

dairy herdsinfectious diseaseMycobacterium avium subsp. paratuberculosisprevalencesouthern Italystatistical analysis

Identifiers

PMID40948933
PMCPMC12425801

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.