ArticleGland surgery2025
Evaluation of the effectiveness of near-infrared autofluorescence (NIRAF) imaging combined with immunocolloidal gold technique (ICGT) in identifying and protecting parathyroid glands during thyroid cancer surgery.
Article in Gland surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The hypocalcemia and hypoparathyroidism due to parathyroid damage during thyroid cancer surgery seriously affect the quality of life of patients. Although contemporary scholars have implemented different technologies, demonstrating improved intraoperative outcomes, there is still a lack of reliable real-time recognition technology. The aim of this study is to assess the efficacy of near-infrared autofluorescence (NIRAF) imaging combined with immunocolloidal gold technique (ICGT) in identifying and protecting parathyroid glands (PTGs) during thyroid cancer surgery. Methods: This retrospective cohort study evaluated 62 thyroid cancer patients undergoing total thyroidectomy with bilateral central lymph node dissection (CLND) by the same surgical team (January-December 2023). Cohort allocation was based on intraoperative identification methods: the observation group (n=34) received NIRAF and ICGT, while the control group (n=28) underwent standard visual assessment. Primary endpoints included (I) intraoperative parathyroid detection quantitation; (II) rates of Results: Intraoperative analysis demonstrated superior glandular preservation in the NIRAF-ICGT cohort, with 128/132 (97.0%) PTGs maintained Conclusions: Compared to traditional visual recognition, the NIRAF-ICGT integrated technology can help surgeons better identify and protect parathyroid function during thyroid cancer surgery.
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