ReviewFrontiers in neuroscience2025
Use of functional magnetic resonance imaging in the evaluation of neural plasticity in macular degeneration.
Review in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Brain-body interactions in systemic diseases: a survey from an imaging perspective.MedScience · 2026Review
- Review of brain-computer interface technology in ophthalmology: Current status, challenges and future directions.Advances in ophthalmology practice and researchReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review evaluates the use of functional Magnetic Resonance Imaging (fMRI) to investigate brain plasticity in Age-Related Macular Degeneration (AMD). An analysis of studies utilizing fMRI methods identified three primary research approaches: task-based fMRI (17 studies), resting-state fMRI (4 studies), and population receptive fields (pRF) with population connective fields modeling (pCF; 3 studies). The review outlines the principles behind each fMRI methodology and summarizes the key functional and morphological findings. Results consistently demonstrated significant structural and connectivity reorganization in the brains of individuals with AMD, suggesting that the brain undergoes adaptive responses to sensory loss. Voxel-based morphometric findings, measuring the gray matter volume loss in visual cortex, further confirm these structural changes, which appear to correlate with altered functional connectivity. These insights underscore the intricate relationship between sensory deficits and cognitive function in AMD and emphasize the potential for targeted therapeutic interventions. FMRI emerges as a vital tool in group studies for understanding the neural underpinnings of AMD and its broader cognitive implications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.