SynthesisFrontiers in neurology2025
Effectiveness of exercise on musculoskeletal function and clinical outcomes in patients with diabetic peripheral neuropathy: a systematic review and meta-analysis.
Synthesis in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- A multimodal manual therapy, exercise, and psychological intervention for painful diabetic neuropathy: the NeuOst feasibility randomised controlled trial.Pain reports · 2026Article
- Review
- Exercise and physical activity interventions in type 2 diabetes mellitus.Frontiers in endocrinology · 2026Review
- Comparison of Intraneural FacilitationBiomedicines · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Diabetes mellitus is a major public health issue, and its complication, diabetic peripheral neuropathy (DPN), can significantly impair foot and ankle joint function, affecting daily activities and quality of life. This systematic review and meta-analysis aimed to evaluate the impact of exercise on musculoskeletal function and clinical outcomes in DPN patients. Methods: Evaluation of randomized controlled trials (RCTs) of exercise in patients with DPN published from Cochrane Library, PubMed, Embase, Web of Science, Medline, ClinicalKey, CNKI, Wanfang database, VIP Chinese Journal Database, and Chinese Biomedical Literature Database was performed. Revman 5.4 software was used for statistical analysis. Results: A total of 625 samples were included in 10 studies. It showed that exercise significantly increased ankle dorsiflexion range of motion (SMD = 0.61, 95%CI (0.13, 1.08), Conclusion: The available evidence suggests that exercise training is an effective method for improving peripheral neuropathy. Systematic review registration: https://inplasy.com/, identifier INPLASY202340112.
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Registered trials
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