Evidence map›Paper›PMID 40948418›Full record

ArticleGut microbes2025

Seeding and feeding: nutrition and birth-associated exposures shape gut microbiome assembly in breastfed infants.

Lisa F Stinson, Isabella Norrish, Faith Mhembere, Ali Sadiq Cheema, Christopher A Mullally, Matthew S Payne, Donna T Geddes

Abstract read
In one paragraph

Article in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lisa F StinsonSchool of Molecular Sciences, The University of Western Australia, Perth, Australia.ORCID 0000-0003-2799-2727
Isabella NorrishSchool of Biomedical Sciences, The University of Western Australia, Perth, Australia.
Faith MhembereSchool of Population and Global Health, The University of Western Australia, Perth, Australia.
Ali Sadiq CheemaGenomics WA, The Kids Research Institute, Perth, Australia.
Christopher A MullallySchool of Medical, Molecular, and Forensic Sciences, Murdoch University, Perth, Australia.ORCID 0000-0001-8071-2523
Matthew S PayneDivision of Obstetrics and Gynaecology, The University of Western Australia, Perth, Australia.ORCID 0000-0002-2308-3561
Donna T GeddesSchool of Molecular Sciences, The University of Western Australia, Perth, Australia.ORCID 0000-0002-0431-7078

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut microbiome establishment in early life is influenced by maternal, infant, and environmental factors, with disruptions linked to later disease risk. Although infant diet is a major determinant of microbial composition, longitudinal data in breastfed infants, particularly in the context of birth interventions, remain limited. We profiled 698 stool samples from 84 predominantly or exclusively breastfed infants in the BLOSOM cohort, spanning 10 time points from 1 week to 2 years of age using full-length 16S rRNA gene sequencing and targeted qPCR. After an initial volatile period, microbiome composition and diversity stabilized between months 2 and 5. Introduction of solid foods then triggered a marked ecological shift, with significant increases in diversity (

Indexed as

BacteriaBreast FeedingGastrointestinal MicrobiomeBifidobacteriumCesarean SectionChild, PreschoolFecesFemaleHumansInfantInfant, NewbornLongitudinal StudiesMaleMilk, HumanRNA, Ribosomal, 16SRNA, Ribosomal, 16Sbreastfeedingdelivery modeInfant gut microbiomeinfant nutritionintrapartum antibiotics

Identifiers

PMID40948418
PMCPMC12439570

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.