Evidence map›Paper›PMID 40948138›Full record

ArticleCirculation research2025

Single-Nucleus RNAseq Defines Cellular and Molecular Landscape of Dysfunctional Right Atrium in Pulmonary Artery Banded Swine.

Jenna B Mendelson, Jacob D Sternbach, Minwoo Kim, Ryan A Moon, Jeffrey C Blake, Rashmi M Raveendran, Lynn M Hartweck, Walt Tollison, Matthew Lahiri, John P Carney and 3 more

Abstract readLetter
In one paragraph

Article in Circulation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Large animal models of right heart failure due to pulmonary hypertension: a bridge to translational success.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jenna B MendelsonDepartment of Integrative Biology and Physiology (J.B.M.), University of Minnesota.ORCID 0000-0002-8229-385X
Jacob D SternbachCardiovascular Division, Department of Medicine, Lillehei Heart Institute (J.D.S., M.K., R.A.M., J.C.B., R.M.R., L.M.H.), University of Minnesota.ORCID 0009-0009-2417-8261
Minwoo KimCardiovascular Division, Department of Medicine, Lillehei Heart Institute (J.D.S., M.K., R.A.M., J.C.B., R.M.R., L.M.H.), University of Minnesota.
Ryan A MoonCardiovascular Division, Department of Medicine, Lillehei Heart Institute (J.D.S., M.K., R.A.M., J.C.B., R.M.R., L.M.H.), University of Minnesota.
Jeffrey C BlakeCardiovascular Division, Department of Medicine, Lillehei Heart Institute (J.D.S., M.K., R.A.M., J.C.B., R.M.R., L.M.H.), University of Minnesota.ORCID 0009-0002-3120-7816
Rashmi M RaveendranCardiovascular Division, Department of Medicine, Lillehei Heart Institute (J.D.S., M.K., R.A.M., J.C.B., R.M.R., L.M.H.), University of Minnesota.ORCID 0009-0001-4384-6036
Lynn M HartweckCardiovascular Division, Department of Medicine, Lillehei Heart Institute (J.D.S., M.K., R.A.M., J.C.B., R.M.R., L.M.H.), University of Minnesota.ORCID 0000-0002-7926-3342
Walt TollisonExperimental Surgical Services, Department of Surgery (W.T., M.L., J.P.C.), University of Minnesota.
Matthew LahiriExperimental Surgical Services, Department of Surgery (W.T., M.L., J.P.C.), University of Minnesota.
John P CarneyExperimental Surgical Services, Department of Surgery (W.T., M.L., J.P.C.), University of Minnesota.ORCID 0000-0002-2090-7764
Felipe KazmirczakAllina Health Minneapolis Heart Institute, Abbott Northwestern Hospital, MN (F.K.).
Gaurav ChoudharyVascular Research Laboratory, Division of Cardiology, Department of Medicine, Providence VA Medical Center, Alpert Medical School of Brown University, RI (G.C.).ORCID 0000-0001-9343-5481
Kurt W PrinsDivision of Cardiology, Department of Medicine, Gazes Cardiac Research Institute, Medical University of South Carolina, Charleston (K.W.P.).ORCID 0000-0002-0364-6742

Funding

GP130 Antagonism in Porcine RV Pressure OverloadR01HL162927 · NHLBI · UNIVERSITY OF MINNESOTA · PI Kurt W Prins · 2022 to 2026
$3.3M
Multi-scale Investigation of Sex Differences in Right Ventricular Function via Estrogen-Microtubule InteractionsR01HL158795 · NHLBI · UNIVERSITY OF MINNESOTA · PI Kurt W Prins · 2022 to 2026
$2.8M
Role of Endothelial Anoctamin-1 in Pulmonary Arterial HypertensionR01HL148727 · NHLBI · OCEAN STATE RESEARCH INSTITUTE, INC. · PI CHOUDHARY, GAURAV · 2019 to 2022
$1.6M
Role of Mitochondrial c-Src in Right Ventricular Dysfunction in Pulmonary HypertensionR01HL169456 · NHLBI · OCEAN STATE RESEARCH INSTITUTE, INC. · PI Gaurav Choudhary, Peng Zhang · 2024 to 2026
$1.3M
Mechanisms of Large Animal RV DysfunctionF31HL170585 · NHLBI · UNIVERSITY OF MINNESOTA · PI MENDELSON, JENNA BLAIR · 2024 to 2025
$71k
NHLBI NIH HHS F31 HL170585NHLBI NIH HHS R01 HL148727NHLBI NIH HHS R01 HL158795NHLBI NIH HHS R01 HL162927NHLBI NIH HHS R01 HL169456
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

atrial functionendoplasmic reticulummacrophagesmitochondria

Identifiers

PMID40948138
PMCPMC12635795

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.