ReviewFuture medicinal chemistry2025
Indole-selenide derivatives: recent advances in design, synthesis and future prospects for therapeutic applications.
Review in Future medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, Selenium (Se) has become an emerging versatile player in medicinal chemistry. Indole scaffolds, known as a "privileged structure," are widely used in drug design due to their unique physicochemical properties and broad biological activities. Indole selenide compounds, which integrate the two important elements of selenium and indole, represent a new and significant structural type and have been reported to exhibit various biological activities, including antitumor, antioxidant and P-glycoprotein inhibitory activities. In this review, we summarize the recent advances in the synthesis, design and biological activity studies of indole-selenide compounds. We also provide perspectives regarding the challenges in indole-selenide-based medicinal chemistry and future research directions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.