Evidence map›Paper›PMID 40947592›Full record

ArticleEuropean psychiatry : the journal of the Association of European Psychiatrists2025

Self-harming behavior linked to earlier onset of cardiovascular disease in severe mental disorders.

Synve Hoffart Lunding, Isabel Viola Kreis, Linn Rødevand, Monica Aas, Maren Caroline Frogner Werner, Ingrid Torp Johansen, Monica Bettina Elkjær Greenwood Ormerod, Elina Reponen, Gabriela Hjell, Petter Andreas Ringen and 6 more

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In one paragraph

Article in European psychiatry : the journal of the Association of European Psychiatrists, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Synve Hoffart LundingDivision of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.ORCID 0000-0002-3342-7997
Isabel Viola KreisInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.ORCID 0000-0002-1022-699X
Linn RødevandInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.ORCID 0000-0001-5967-6601
Monica AasSocial, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Maren Caroline Frogner WernerDepartment of Research and Innovation, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.ORCID 0000-0003-0988-5223
Ingrid Torp JohansenInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.ORCID 0000-0001-7976-1395
Monica Bettina Elkjær Greenwood OrmerodDivision of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.ORCID 0000-0002-8183-5530
Elina ReponenDivision of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Gabriela HjellDepartment of Psychiatry, Ostfold Hospital, Graalum, Norway.ORCID 0000-0002-1257-6731
Petter Andreas RingenDivision of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.ORCID 0000-0002-8308-6713
Trine Vik LagerbergDivision of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Ingrid MelleDivision of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.ORCID 0000-0002-9783-548X
Ole Andreas AndreassenDivision of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Carmen SimonsenDepartment of Psychology, University of Oslo, Oslo, Norway.ORCID 0000-0002-5083-5706
Torill UelandDivision of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Nils Eiel SteenDivision of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.ORCID 0000-0001-6442-1179

Funding

Helse Sør-Øst RHF #2017-112, #2019-108Stiftelsen Kristian Gerhard Jebsen
6 · The paper itself

Abstract

backgroundPeople with severe mental disorders (SMDs) have about 15 years shorter life expectancy than the general population. Cardiovascular disease (CVD) is among the leading causes of premature mortality and shares genetic underpinnings with SMDs. We investigated the link between clinical traits in SMDs and time to the first CVD diagnosis.

methodsThe study included 1,627 well-characterized participants with schizophrenia spectrum (SCZ,

resultsAmong individuals with SMD, recurring self-harming behavior (SHB) was associated with a shorter time to first CVD diagnosis (

conclusionsSHB and a history of suicide attempts in individuals with SMD seem to be associated with earlier CVD onset, and may improve the prediction of CVD, in addition to standard cardiovascular risk factors.

Indexed as

Bipolar DisorderCardiovascular DiseasesSchizophreniaSelf-Injurious BehaviorAdultAge of OnsetComorbidityFemaleHumansMaleMiddle AgedNorwayRegistriesSuicide, Attemptedattempted suicidebipolar disorderscardiovascular disease riskregistry dataschizophreniaself-harm

Identifiers

PMID40947592
PMCPMC12538181

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.