Evidence map›Paper›PMID 40947571›Full record

ArticleVeterinary ophthalmology2026

Comparison of Rebound and Applanation Tonometry in Eyes With Focal Corneal Edema.

Julie A Kiland, Hannah M Terhaar, Hannah E Walleck, Nickolas Chen, Odalys Torné, Kazuya Oikawa, Tina Wahl, Gillian J McLellan

Abstract readComparative Study
In one paragraph

Article in Veterinary ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Julie A KilandDepartment of Ophthalmology and Visual Sciences, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID https://orcid.org/0000-0002-9019-2346
Hannah M TerhaarDepartment of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID https://orcid.org/0000-0003-3651-9448
Hannah E WalleckDepartment of Ophthalmology and Visual Sciences, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Nickolas ChenDepartment of Ophthalmology and Visual Sciences, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Odalys TornéDepartment of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Kazuya OikawaDepartment of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID https://orcid.org/0000-0003-2202-4786
Tina WahlDepartment of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Gillian J McLellanDepartment of Ophthalmology and Visual Sciences, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.

Funding

UW Vision Research Core - Administrative CoreP30EY016665 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI Donna M Peters · 2005 to 2026
$12.6M
NEI NIH HHS P30 EY016665NIH HHSResearch to Prevent Blindness
6 · The paper itself

Abstract

objectiveTo determine the effect of corneal edema on intraocular pressure (IOP) readings and their accuracy and precision when obtained with handheld rebound and applanation tonometers. ANIMALS AND PROCEDURES: IOP readings from areas of focal corneal edema were compared to those from clear cornea in 10 eyes of 7 glaucomatous cats in vivo using TONOVET Plus (TVP) and TONOVET (TV01) rebound, and Tono-Pen Vet (TP) applanation tonometers. Four different feline eyes with focal corneal edema were cannulated ex vivo and tonometry readings obtained from clear and edematous cornea at set manometric IOPs from 5 to 70 mmHg.

resultsRebound tonometry values were 4.0 ± 5.5 (SD) mmHg lower, and TP values were 13.0 ± 5.9 (SD) mmHg higher in regions of edema versus clear cornea in the same eye (p = 0.0075). Relative to manometry, TVP and TV01 accuracy and precision were acceptable for clear cornea readings but were negatively impacted by corneal edema. TP-derived readings grossly underestimated high IOPs relative to manometry in both clear and edematous feline cornea and were significantly less accurate than rebound tonometers in clear cornea (p = 0.03). All tonometers were less precise in edematous cornea; the TP was significantly less precise than the TV01 (p = 0.0419).

conclusionsAlthough IOP values obtained with the TVP and TV01 tend to be less accurate and precise in edematous versus clear cornea, rebound tonometry is impacted by corneal edema to a lesser degree than applanation tonometry. In patients with corneal edema, IOP measurements should be obtained from clear corneal regions when possible.

Indexed as

Cat DiseasesCorneal EdemaTonometry, OcularAnimalsCatsFemaleIntraocular PressureMaleapplanation tonometrycorneal edemafelineglaucomaintraocular pressurerebound tonometry

Identifiers

PMID40947571
PMCPMC12717628

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.