Evidence map›Paper›PMID 40947437›Full record

ArticleMikrochimica acta2025

An all-in-one assay for bacteria-related detections through gold nanoparticles-amplified electrical conductivity.

Shicheng Su, Jing Hu, Yichun Zhu, Bing Liang, Yaping Zhu, Shuifeng Zhang, Huadong Sheng, Hongbo Chen, Yunlei Xianyu, Chunyan He

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shicheng Su *Department of Respiratory Medicine, Kunshan Hospital of Chinese Medicine, Affiliated Hospital of Yangzhou University, Suzhou, 215300, Jiangsu, China.
Jing Hu *College of Biosystems Engineering and Food Science, Zhejiang University Hangzhou, Zhejiang, 310058, China.
Yichun ZhuDepartment of Clinical Laboratory, Kunshan Hospital of Chinese Medicine, Affiliated Hospital of Yangzhou University, Suzhou, Jiangsu, 215300, China.
Bing LiangDepartment of Respiratory Medicine, Kunshan Hospital of Chinese Medicine, Affiliated Hospital of Yangzhou University, Suzhou, 215300, Jiangsu, China.
Yaping ZhuDepartment of Clinical Laboratory, Kunshan Hospital of Chinese Medicine, Affiliated Hospital of Yangzhou University, Suzhou, Jiangsu, 215300, China.
Shuifeng ZhangNational Pre-packaged Food Quality Supervision and Inspection Center (Zhejiang), Zhejiang Fangyuan Test Group Co. LTD., Hangzhou, 310018, China.
Huadong ShengNational Pre-packaged Food Quality Supervision and Inspection Center (Zhejiang), Zhejiang Fangyuan Test Group Co. LTD., Hangzhou, 310018, China.
Hongbo ChenNational Pre-packaged Food Quality Supervision and Inspection Center (Zhejiang), Zhejiang Fangyuan Test Group Co. LTD., Hangzhou, 310018, China.
Yunlei XianyuCollege of Biosystems Engineering and Food Science, Zhejiang University Hangzhou, Zhejiang, 310058, China. xianyu19@zju.edu.cn.
Chunyan HeDepartment of Clinical Laboratory, Kunshan Hospital of Chinese Medicine, Affiliated Hospital of Yangzhou University, Suzhou, Jiangsu, 215300, China. chunyanhe530@163.com.

Funding

Key Research and Development Program of Zhejiang Province 2025C02124Natural Science Foundation of Jiangsu Province BK20241825
6 · The paper itself

Abstract

An all-in-one assay based on the electrical conductivity (EC) has been developed that enables the viability test and the specific detection of pathogenic bacteria, including the differentiation of (1) live/dead bacteria, (2) drug-sensitive/resistant bacteria, (3) Gram-positive/negative bacteria, and (4) specific detection of A. baumannii. Key to this assay is the modification of gold nanoparticles on the surface of bacteria that can amplify the EC signal for enhanced sensitivity and rapid detection. The amplification effect of gold nanoparticles significantly reduces the time and enhances the sensitivity for bacteria detection. This EC-based assay outcompetes traditional colorimetric and fluorescent methods owing to its rapid response, convenient operation, and low cost, which holds great promise for biosensing.

Indexed as

BacteriaBiosensing TechniquesElectric ConductivityGoldMetal NanoparticlesAcinetobacter baumanniiGoldBacteria detectionElectrical conductivityGold nanoparticlesViability test

Identifiers

PMID40947437

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.