Evidence map›Paper›PMID 40947126›Full record

ArticlePhytotherapy research : PTR2025

Herbal Medicines for Weight Loss and Lipid Profile Improvement: A Scoping Review of Therapeutic Effects and Safety.

Marcela Forgerini, Geovana Schiavo, Osvaldo Galo Neto, Gabriela Barbosa Nascimento, Johnny Wallef Leite Martins, Patrícia de Carvalho Mastroianni

Abstract readScoping Review
In one paragraph

Article in Phytotherapy research : PTR, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marcela ForgeriniDepartment of Drugs and Medicines, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, Brazil.ORCID https://orcid.org/0000-0002-2905-8519
Geovana SchiavoDepartment of Drugs and Medicines, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, Brazil.ORCID https://orcid.org/0000-0001-9502-6155
Osvaldo Galo NetoDepartment of Drugs and Medicines, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, Brazil.ORCID https://orcid.org/0000-0002-2028-5133
Gabriela Barbosa NascimentoDepartment of Drugs and Medicines, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, Brazil.ORCID https://orcid.org/0000-0002-2046-3745
Johnny Wallef Leite MartinsDepartment of Drugs and Medicines, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, Brazil.ORCID https://orcid.org/0000-0002-0391-8656
Patrícia de Carvalho MastroianniDepartment of Drugs and Medicines, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, Brazil.ORCID https://orcid.org/0000-0001-8467-7278

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 124803/2022-9Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001Fundação de Amparo à Pesquisa do Estado de São Paulo 2022/14307-0Fundação de Amparo à Pesquisa do Estado de São Paulo 2022/14640-0
6 · The paper itself

Abstract

The demand for alternative weight loss therapies has surged, with herbal medicinal products gaining popularity due to their natural origins, perceived safety, and accessibility. However, evidence regarding their therapeutic effects and safety for weight loss remains limited. Thefore, this study aimed to identify herbal medicines used for weight loss and their efficacy and safety. A scoping review was conducted using PubMed, Embase, Scopus, and LILACS databases (September 2023). Studies evaluating the efficacy and safety of herbal medicines for weight loss in individuals aged 18 years or older were included. Study selection and data extraction were performed independently by two reviewers. A total of 74 studies involving 5508 participants were included. Most studies were double-blind randomized clinical trials (n = 50) and conducted in participants diagnosed with overweight and/or obesity (n = 70), predominantly in Asia (n = 40). The duration of interventions ranged from 10 to 613 days. The most frequently evaluated herbal medicines were Camellia sinensis (n = 16), Ephedra sp. (n = 13), Garcinia cambogia (n = 9), Citrus sp. (n = 5), and Glycyrrhiza sp. (n = 5). Five studies conducted post-intervention follow-ups. Only 10 studies did not report improvements in any parameter. Adverse events ranged from mild symptoms (e.g., headache) to severe reactions (e.g., increased blood pressure), with Ephedra sp. being linked to the most serious events. In conclusion, herbal medicinal products may offer benefits for weight loss. However, their use should be approached cautiously due to potential safety concerns.

Indexed as

LipidsObesityPhytotherapyPlant PreparationsWeight LossAnti-Obesity AgentsHumansOverweightPlants, MedicinalRandomized Controlled Trials as TopicAnti-Obesity AgentsLipidsPlant Preparationsanti‐obesity agentsherbal preparationspatient safetyphytotherapeutic drugsweight reductions

Identifiers

PMID40947126
PMCPMC12504802

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.