ArticleEnvironmental research2025
Ambient air pollution and incident dementia: exploration of relevant exposure windows.
Article in Environmental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- The sex-specific association between long-term PM2.5 exposure and incident dementia in community-dwelling older adults in Australia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
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Authors and funding
10 authors.
Funding
Abstract
backgroundAs dementia has a decades-long preclinical phase, earlier air pollution exposures may be more etiologically relevant to dementia risk than more recent exposures.
methodsWe estimated exposures at Atherosclerosis Risk in Communities (ARIC) study participant addresses to criteria air pollutants, PM components, and trace metals in several exposure windows (1990-1994, 1995-1999, 2000-2004, 2005-2009, and 1990-2009) using a chemical transport model with observation data fusing at two resolutions, 4 km (CTM-4k) and finest available resolution (CTM-FR), and to PM
resultsDuring follow-up (mean: 6.1 years) of 5,621 participants (mean baseline age: 76 years), 828 (14.7 %) developed dementia. Analyses did not support an association between most air pollutant exposures in any exposure window and incident dementia. However, we observed stronger associations in later time periods for PM DISCUSSION: We found little evidence supporting the hypothesized greater etiologic relevance of earlier exposures on incident dementia. Spatial confounding or acceleration of pathologic processes may explain the stronger associations observed with later exposure windows.
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