Evidence map›Paper›PMID 40946621›Full record

ArticleInternational journal of surgery case reports2025

Bilateral neglected facial invasive squamous cell carcinoma in an 89-year-old man, complete excision and primary reconstruction by cervicofacial flap, case report and review of current reconstruction approaches.

Amin Rezazadeh, Ali Samady Khanghah, Sonia Sharifi Namin

Abstract readCase Reports
In one paragraph

Article in International journal of surgery case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Amin RezazadehDepartment of Plastic and Reconstructive Surgery, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran. Electronic address: aminrezazadeh50@yahoo.com.
Ali Samady KhanghahDepartment of Surgery, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran. Electronic address: alisamady89@yahoo.com.
Sonia Sharifi NaminDepartment of Pathology, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran. Electronic address: sonya_shn@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and importanceNon-melanoma skin neoplasms generally account for more than 80 % of occur in people in their 7th decade of life or higher, and increasing prevalence has made them a global concern. Squamous cell carcinoma (SCC) is the first step of the group of neoplasms mentioned above. An appearance of typical cutaneous squamous cell carcinoma (CSCC) is a non-healing, usually progressively enlarging erythematous papule, plaque, or ulcer. For cosmetic reasons, the surgeon should excise such lesions and then schedule second or third operations for flap-mediated reconstructions. CASE PRESENTATION: After reporting a novel case of bilateral neglected facial invasive SCC affecting the parotid region in an 89-year-old man whose treatment with a semi-therapeutic palliative approach, we have conducted a review of facial CSCC from the aspects of epidemiology, staging, and therapeutic management. CLINICAL DISCUSSION: Despite mucosal SCC, cutaneous ones rarely metastasized, varying from 0.5 to 10 %. Subdividing primary cutaneous SCC into low and high-risk types has been of interest over the last decade since they behave differently regarding regional metastasis, resulting in prognosis differences. Most cutaneous SCC includes previously untreated small (less than 2 cm), thin (less than 2 mm), and well-differentiated cases.

conclusionsThe surgeons should weigh against the outcome of their approach. For instance, in the case of older people and the risk of multiple general anesthesia, a palliative approach can be considered.

Indexed as

Cervicofacial flapParotidSquamous cell carcinoma

Identifiers

PMID40946621
PMCPMC12496519

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.