ArticleAnnals of medicine2025
Allergic rhinitis and behaviour problems in urban children aged 6 to 12 years and the mediating role of sleep disturbance.
Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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14 authors.
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Abstract
backgroundThe association between allergic rhinitis (AR) and behaviour problems (BPs) is still controversy. Furthermore, potential critical mediating role of sleep disturbance (SD) in their association has not been explored.
methodsA total of 18,316 children aged 6 to 12 (mean age 7.89 years, male: 53.1%) were recruited from 34 primary schools from Shanghai, China. Demographic information, medical history, Children's Sleep Habits Questionnaire (CSHQ), and Conners' Parent Rating Scale (CPRS) were reported or scored by guardians
resultsThe prevalence of AR, SD and any BP was 32.9%, 23.3% and 18.0%, respectively. Adjusted odds ratios (ORs) for BPs were significantly higher in children with AR compared to those without (all CONCLUSIONS AND RELEVANCE: Children with AR have higher odds of presenting BPs, and SD significantly mediates these associations. These results highlight the importance of proper screening and management of SD and BPs in urban children with AR.
trial registrationregistration name (Effect of OSAHS on cognitive behavioural dysfunction in school-aged children: a large-scale prospective cohort study); registration number (ChiCTR1800014488); URL of the registry (https://www.chictr.org.cn/showproj.html?proj=24763).
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