Evidence map›Paper›PMID 40946157›Full record

ArticleThe American journal of case reports2025

Management of Complex Anal Fistula in Recurrent Perianal Abscess: A Case Report.

Mingzi Zhang, Wei Wang, Yijun Xia, Huaqing Zhang, Yue Du, Zhi Wang, Xiao Long

Abstract readCase Reports
In one paragraph

Article in The American journal of case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mingzi ZhangDepartment of Plastic Surgery, Peking Union Medical College Hospital, Beijing, China.
Wei WangDepartment of Emergency, Qingdao Huangdao District Hospital of Traditional Chinese Medicine, Qingdao, Shandong, China.
Yijun XiaDepartment of Plastic Surgery, Peking Union Medical College Hospital, Beijing, China.
Huaqing ZhangDepartment of General Surgery, Peking Union Medical College Hospital, Beijing, China.
Yue DuDepartment of Dermatology, Qingdao Huangdao District Hospital of Traditional Chinese Medicine, Qingdao, Shandong, China.
Zhi WangDepartment of Plastic Surgery, Peking Union Medical College Hospital, Beijing, China.
Xiao LongDepartment of Plastic Surgery, Peking Union Medical College Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Perianal abscesses are acute suppurative infections in perianal soft tissues or spaces, frequently associated with Crohn's disease, malignancies, diabetes, immunosuppression, or prior anorectal procedures. Persistent or recurrent infections following incision and drainage (I&D) with standard wound care may indicate occult anal fistulas, necessitating thorough evaluation. CASE REPORT A 32-year-old woman presented with acute right buttock/thigh swelling, pain, and hypotension, initially diagnosed as septic shock. No predisposing factors were identified. Initial management included antibiotics and CT-guided drainage, resolving symptoms temporarily. One month later, she developed recurrent fever, chills, and a subcutaneous abscess. Repeated evaluations revealed no fistula; I&D with vacuum sealing drainage (VSD) and plastic surgery-led wound closure achieved transient improvement. Three months postoperatively, purulent discharge recurred. Persistent symptoms prompted referral to a colorectal hospital. Rectal MRI identified a high complex-type anal fistula, confirmed surgically. Definitive fistula repair led to complete resolution. CONCLUSIONS Recurrent perianal infections, particularly in diabetics or obese patients, require vigilance for occult fistulas. This case highlights the bidirectional relationship between abscesses and fistulas, emphasizing that negative initial evaluations do not exclude fistula formation. MRI demonstrates superior diagnostic accuracy for complex fistulas and should be prioritized in refractory cases. Repeated drainage without addressing underlying fistulous tracts lacks long-term effectiveness. Early multidisciplinary collaboration and definitive surgical intervention are critical for sustained recovery. Specialized imaging and timely referrals optimize outcomes in diagnostically challenging scenarios.

Indexed as

AbscessAnus DiseasesRectal FistulaAdultAnti-Bacterial AgentsDrainageFemaleHumansMagnetic Resonance ImagingRecurrenceAnti-Bacterial Agents

Identifiers

PMID40946157
PMCPMC12445932

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.