ArticleCJEM2025
The U-POCUS protocol: urinalysis and point-of-care ultrasound to exclude symptomatic ureterolithiasis in emergency department patients.
Article in CJEM, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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8 authors.
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Abstract
objectiveUrolithiasis is a common urological condition accounting for more than 1.3 million emergency department visits annually with costs exceeding $2.8 billion (Scales et al. in Eur Urol. 62:160-5, 2012;Eaton et al. in J Endourol 27:1535-1538, 2013;Antonelli et al. in Eur Urol 66:724-729, 2014;). Non-contrast computed tomography of the abdomen and pelvis remains the diagnostic gold standard. Studies assessing urinalysis and renal point-of-care ultrasound (PoCUS), individually, to diagnose symptomatic ureterolithiasis demonstrate inadequate sensitivities (Mefford et al. in West J Emerg Med 18:775, 2017;Eray et al. in Am J Emerg Med 21:152-4, 2003;Luchs et al. in Urology 59:839-842, 2002;Smith-Bindman et al. in N Engl J Med 371:1100-1110, 2014;Riddell et al. in West J Emerg Med 15:96-100, 2014;Rosen et al. in J Emerg Med 16:865-870, 1998;Gaspari and Horst in Acad Emerg Med 12:1180-1184, 2005;Watkins et al. in Emerg Med Australas 19:188-195, 2007;). The primary objective of this study was to assess the test characteristics of the U-PoCUS (urinalysis with renal point-of-care ultrasound) protocol.
methodsThis was an Institutional Review Board approved, multi-center, retrospective chart review at a university-based healthcare system. Study investigators included all patients who presented from January 1, 2016 through June 30, 2020, and underwent computed tomography of the abdomen and pelvis and had a urinalysis and PoCUS for suspected ureterolithiasis. Investigators utilized MedCalc (Version 19.1.6) and standard 2 × 2 tables to calculate test characteristics with 95% confidence intervals (CI).
resultsStudy investigators enrolled 183 patients, including 122 patients diagnosed with computed tomography confirmed ureterolithiasis and 61 patients without it. The combination of hematuria and/or hydronephrosis on PoCUS had a sensitivity of 99.2% (95.6-100) and a specificity of 14.8% (7-26.2) for the presence of urolithiasis. Positive predictive value and negative predictive value were 69.9% (67.7-72.1) and 90% (53.9-98.6), respectively.
conclusionThe presence of hematuria and/or hydronephrosis was 99.2% sensitive for the presence of ureterolithiasis diagnosed on computed tomography of the abdomen and pelvis. The U-PoCUS protocol missed only one symptomatic ureterolithiasis.
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