Evidence map›Paper›PMID 40946125›Full record

ArticleAnnals of surgical oncology2026

Impact of Screening Mammography on Breast Cancer Outcomes in Women Aged 80 Years and Over.

Siu-Yuan Huang, Makaelah Murray, Angelique Rubio, Nneoma Okoro, Mina S Sedrak, Susan A McCloskey, Nicholas Jackson, Mediget Teshome, Nimmi S Kapoor

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Siu-Yuan HuangDepartment of Surgery, Division of Surgical Oncology, University of California, Los Angeles, Los Angeles, CA, USA.
Makaelah MurrayDavid Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Angelique RubioDivision of Health Services Research, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Nneoma OkoroDavid Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Mina S SedrakDepartment of Medicine, Division of Hematology and Oncology, University of California, Los Angeles, Los Angeles, CA, USA.
Susan A McCloskeyDepartment of Radiation Oncology, University of California, Los Angeles, Los Angeles, CA, USA.
Nicholas JacksonDivision of Health Services Research, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Mediget TeshomeDepartment of Surgery, Division of Surgical Oncology, University of California, Los Angeles, Los Angeles, CA, USA.
Nimmi S KapoorDepartment of Surgery, Division of Surgical Oncology, University of California, Los Angeles, Los Angeles, CA, USA. nskapoor@mednet.ucla.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAge remains a significant risk factor for breast cancer, yet specific breast cancer screening guidelines for women > 75 years of age are not clearly defined. We sought to compare differences in outcomes among breast cancer patients diagnosed at ≥ 80 years of age based on receipt of screening mammography.

methodsThis single-institution retrospective review identified breast cancer patients diagnosed at ≥ 80 years of age from 2013 to 2020. The screened cohort underwent screening mammography within 2 years of diagnosis. Characteristics of the screened/unscreened cohorts were compared using Chi-square and t-tests. Kaplan-Meier survival analysis and log-rank testing were performed to compare overall survival (OS) and disease-free survival (DFS). Cox proportional hazard models produced unadjusted/adjusted hazard ratios (HRs) to estimate the association of receiving a screening mammogram with OS/DFS.

resultsOf 174 patients, 98 were screened and 76 were unscreened. Median age was 83 years, most patients had stage I/II tumors, and most cancers were estrogen receptor-positive/human epidermal growth factor receptor 2-negative. The groups did not significantly differ in race/ethnicity, comorbidities, receptor subtype, axillary surgery, or receipt of endocrine therapy/chemotherapy. Unscreened patients were more likely to have tumors that were palpable, high grade, and advanced stage. More screened patients underwent lumpectomy, while more unscreened patients omitted surgery. With a median follow-up of 55 months, the screened cohort had improved DFS (HR 0.45, 95% confidence interval [CI] 0.301-0.665; p < 0.001) and OS (HR 0.26, 95% CI 0.126-0.544; p < 0.001). This persisted when adjusted for age, receptor subtype, and surgery.

conclusionsBreast cancer patients diagnosed at ≥ 80 years of age who received screening mammography presented with earlier-stage disease and had improved DFS and OS compared with the unscreened cohort.

Indexed as

Breast NeoplasmsEarly Detection of CancerMammographyAged, 80 and overFemaleFollow-Up StudiesHumansPrognosisRetrospective StudiesSurvival RateAdvanced ageBreast cancerBreast cancer screeningPatient outcomesScreening mammography

Identifiers

PMID40946125
PMCPMC12689825

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.