SynthesisJournal of gastrointestinal cancer2025
Comparative Efficacy of Thermal Ablation and Surgical Resection in Patients with Colorectal Cancer Liver Metastasis: A Systematic Review and Meta-analysis.
Synthesis in Journal of gastrointestinal cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- MicroRNA-345-3p expression inhibits colorectal cancer liver metastasis by targeting KHDRBS1 and TGF-β signaling pathway.Hereditas · 2026Article
- Thermal Ablation for Colorectal Liver Metastases: Current Evidence and Future Horizons.Diagnostics (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeColorectal cancer (CRC) often involves liver. However, the standard treatment for CRC with liver metastases (CRC-LM) is debatable. This meta-analysis compares the efficacy of ablation with surgical resection in CRC-LM patients.
methodsA systematic literature search was conducted in PubMed, ClinicalTrials.gov and Cochrane Library. Studies published during January 2020 to February 2025 and comparing any form of ablation with surgical resection in adult patients with CRC-LM were included. The primary outcomes were overall survival (OS), disease-free survival (DFS), while the secondary outcomes were recurrence patterns, length of hospital stay, and complication rates.
resultsA total of 15 studies were included in the meta-analysis. The pooled analysis revealed a significant difference in OS favoring surgical resection (RR: 0.82, 95% CI: 0.73, 0.92, p = 0.001, I
conclusionSurgical resection offered superior OS compared to thermal ablation for CRC-LM patients. However, thermal ablation was associated with shorter hospital stay and fewer major complications, highlighting its value as a less invasive alternative in selected patients.
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Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.