ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2025
Wormian bones in simple sagittal synostosis: incidence and correlations.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWormian bones are accessory cranial bones of interest to neurosurgeons, radiologists, and anthropologists. Its origin is attributed to alteration in deformational forces. Sagittal synostosis alters normal cranial development and is a suitable model to explore the role of mechanical forces in wormian bone development. We aim to study the incidence and clinical correlations of wormian bones in patients with isolated sagittal synostosis operated on at Hospital La Fe in the past 10 years.
methodsWe retrospectively reviewed clinical and radiological data from patients with isolated sagittal synostosis treated at Hospital La Fe over the past 10 years. Demographic and clinical data were collected. Preoperative CT scans, including 3D reconstructions and MIP images, were assessed for anterior fontanelle and metopic suture patency, sagittal suture fusion, presence of apical wormian bones, and anthropometric measurements.
resultsA total of 104 patients (80 males, 24 females) were included. Mean age at diagnosis was 3.72 months; average cranial index was 0.64. Complete anterior fontanelle and metopic suture closure were observed in nine and 24 patients, respectively. Apical wormian bones were present in 41 patients. Fontanelle and metopic suture closure followed an age-dependent pattern. However, wormian bone presence was independent of age but significantly associated with occipital incline.
conclusionsApical wormian bones are frequently observed in sagittal synostosis. Their presence may reflect a compensatory response to altered cranial forces and correlates with occipital morphology. Apical wormian bones need not be included in the surgical resection plan.
Indexed as
Identifiers
40946092What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.