Evidence map›Paper›PMID 40945957›Full record

Observational studyThe Journal of international medical research2025

Postoperative delirium after short-acting spinal anesthesia and general anesthesia after shared decision-making.

Valesca Kipping, Timo B Kerlin, Friedrich Borchers, Margret F Külken, Marilena Schmid, Christopher S Ahrend, Janine Wiebach, Sophie K Piper, Klaus D Wernecke, Anika Müller and 1 more

Abstract readObservational Study
In one paragraph

Observational study in The Journal of international medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Valesca KippingDepartment of Anesthesiology and Intensive Care Medicine, Charité - Universitätsmedizin Berlin, Germany.ORCID 0009-0003-4569-7665
Timo B KerlinDepartment of Anesthesiology and Intensive Care Medicine, Charité - Universitätsmedizin Berlin, Germany.ORCID 0009-0003-5231-0350
Friedrich BorchersDepartment of Anesthesiology and Intensive Care Medicine, Charité - Universitätsmedizin Berlin, Germany.
Margret F KülkenDepartment of Anesthesiology and Intensive Care Medicine, Charité - Universitätsmedizin Berlin, Germany.
Marilena SchmidDepartment of Anesthesiology and Intensive Care Medicine, Charité - Universitätsmedizin Berlin, Germany.
Christopher S AhrendDepartment of Anesthesiology and Intensive Care Medicine, Charité - Universitätsmedizin Berlin, Germany.
Janine WiebachBerlin Institute of Health at Charité - Universitätsmedizin Berlin, BIH Metabolomics, Germany.
Sophie K PiperInstitute of Biometry and Clinical Epidemiology, Charité - Universitätsmedizin Berlin, Germany.
Klaus D WerneckeInstitute of Biometry and Clinical Epidemiology, Charité - Universitätsmedizin Berlin, Germany.
Anika MüllerDepartment of Anesthesiology and Intensive Care Medicine, Charité - Universitätsmedizin Berlin, Germany.
Claudia D SpiesDepartment of Anesthesiology and Intensive Care Medicine, Charité - Universitätsmedizin Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectivePrevious studies have shown that the postoperative delirium rate does not differ between anesthetic techniques in randomized controlled trials. Subjective concerns such as anxiety and pain are often not adequately addressed in randomized controlled trials and reported to be associated with postoperative delirium. Shared decision-making is reported to have an impact on anxiety and pain. Therefore, the aim of this study was to evaluate the effect of shared decision-making while making a choice between spinal and general anesthesia on postoperative delirium incidence.MethodsThis prospective, observational, two-armed cohort study included 192 patients who underwent lower extremity, lower abdominal, pelvic, or perineal short-time surgery that lasted <90 min. The three-talk shared decision-making model was used to make the choice for the type of anesthesia. Depending on the shared decision-making process, either spinal anesthesia with short-acting local anesthetics (prilocaine hydrochloride or chloroprocaine hydrochloride) or general anesthesia was performed according to a standardized protocol including intraoperative electroencephalogram monitoring. Patients' anxiety and pain levels were measured before and after the surgery using validated scales.ResultsBased on their shared decision-making choice of anesthesia, 97 patients were allocated to the spinal anesthesia group and 95 to the general anesthesia group. Postoperative delirium occurred less frequently after spinal anesthesia (2.1%) than after general anesthesia (16.8%; p < 0.001). No postoperative delirium was observed in patients who received only spinal anesthesia, as chosen using the shared decision-making model (spinal anesthesia: 0%, general anesthesia 16.8%; p < 0.001). Anxiety and pain levels did not differ between the two groups.ConclusionsThe incidence of postoperative delirium was lower in patients who were administered spinal anesthesia than in those who were administered general anesthesia after using a shared decision-making approach. Integrating patients' perspectives and treatment preferences might change postoperative outcomes and should be taken into consideration in future trials.

Indexed as

Anesthesia, GeneralAnesthesia, SpinalDecision Making, SharedDeliriumEmergence DeliriumPostoperative ComplicationsAdultAgedAnxietyFemaleHumansIncidenceMaleMiddle AgedProspective StudiesPostoperative deliriumshared decision-makingshort-acting local anestheticsspinal anesthesia

Identifiers

PMID40945957
PMCPMC12433544

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.