Evidence map›Paper›PMID 40945922›Full record

ArticleJournal of the American Medical Directors Association2025

Frailty Status and Dysphagia Trajectory Among Hospitalized Nursing Home Residents With Advanced Dementia.

Raele Donetha Loy, Rebecca Howe, Sweta Patel, Nicole Rogus-Pulia, James L Rudolph

Abstract read
In one paragraph

Article in Journal of the American Medical Directors Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Raele Donetha LoyCenter for Health Disparities Research, University of Wisconsin-Madison, Madison, WI, USA. Electronic address: rloy2@wisc.edu.
Rebecca HoweTransformative Health Systems Research to Improve Veteran Equity and Independence Center of Innovation (THRIVE COIN), Providence VA Medical Center, Providence, RI, USA; Warren Alpert Medical School of Brown University, Providence, RI, USA.
Sweta PatelCenter for Gerontology and Health Care Research, Brown University School of Public Health, Providence, RI, USA.
Nicole Rogus-PuliaCenter for Health Disparities Research, University of Wisconsin-Madison, Madison, WI, USA; Department of Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, Madison, WI, USA; Geriatric Research Education and Clinical Center, William S. Middleton Memorial Veterans Hospital, Madison, WI, USA.
James L RudolphTransformative Health Systems Research to Improve Veteran Equity and Independence Center of Innovation (THRIVE COIN), Providence VA Medical Center, Providence, RI, USA; Warren Alpert Medical School of Brown University, Providence, RI, USA; Center for Gerontology and Health Care Research, Brown University School of Public Health, Providence, RI, USA.

Funding

VARIATIONS IN LIFE'S FINAL CHAPTERP01AG027296 · NIA · BROWN UNIVERSITY · PI AMAL N. TRIVEDI · 2007 to 2026
$38.9M
Swallowing Trajectories and DysPHagia Predictors in AlzheimER’s DisEase (SPHERE)R01AG082170 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Nicole M Rogus-Pulia · 2023 to 2026
$3.0M
Impact of Novel Rehabilitative Approaches FOR Dysphagia in Patients with Alzheimer's Disease and Related DementiasK76AG068590 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI ROGUS-PULIA, NICOLE M · 2020 to 2023
$1.3M
The Role of Homeostenosis in Bulbar Function in ALS and AgingK00AG076123 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI LOY, RAELE DONETHA · 2021 to 2024
$336k
NIA NIH HHS K00 AG076123NIA NIH HHS K76 AG068590NIA NIH HHS P01 AG027296NIA NIH HHS R01 AG082170
6 · The paper itself

Abstract

objectiveThe objective of this analysis was to describe the association of dysphagia and frailty in persons living with dementia (PLWD) residing in skilled nursing facilities (SNFs) who experienced hospitalization.

designRetrospective cohort. SETTING AND

participantsLong-stay US nursing home residents from 2012-2018 with advanced dementia who experienced a hospitalization.

methodsAmong the cohort, we captured Minimum Data Set (MDS) assessments of dysphagia before and after hospitalization. MDS items were also used to measure FRAIL-NH (fatigue, resistance, ambulation, incontinence, weight loss, nutritional approach, help with dressing) scale components before hospitalization. Adjusted analyses identified the risk for dysphagia in the pre-hospital cohort and new dysphagia in the post-hospital cohort according to pre-hospital frailty status.

resultsAmong the pre-hospital cohort (n = 1,207,345), 85% (n = 1,026,736) were classified as frail. Almost half of the cohort (n = 562,574, 46.6%) was on a mechanically altered diet. Dysphagia frequency was higher among frail residents (6.2% vs 2.4% prefrail vs 1.1% nonfrail). After adjustment for demographics and comorbidities, frailty was associated with greater risk of dysphagia [adjusted incidence rate ratio (IRR), 3.97; 95% CI, 3.49-4.49]. Among those who survived hospitalization (n = 1,078,321), frailty was also associated with new dysphagia (adjusted IRR, 1.7; 95% CI, 1.6-1.7). CONCLUSIONS AND IMPLICATIONS: Frailty is associated with increased risk of dysphagia among PLWD residing in SNFs. Additionally, frail PLWD who experience hospitalization are at increased risk of new dysphagia. These results have important implications for designing interventions to decrease dysphagia among frail PLWD. Given the wide disparity between the rates of mechanically altered diets and dysphagia as determined by MDS items, additional validation studies on the use of the MDS in dysphagia are warranted.

Indexed as

Deglutition DisordersDementiaFrail ElderlyFrailtyHospitalizationNursing HomesAgedAged, 80 and overFemaleGeriatric AssessmentHumansMaleRetrospective StudiesUnited StatesdementiadysphagiaFrailty

Identifiers

PMID40945922
PMCPMC12690973

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.