Evidence map›Paper›PMID 40944630›Full record

ArticleAmerican journal of hematology2025

Third-Generation Bruton tyrosine kinase Inhibitors for the Treatment of Monoclonal Gammopathy of Thrombotic Significance (MGTS).

Louise Man, Adam J Kanack, Emily E Mauch, Noah P Splinter, Anand Padmanabhan

Abstract readLetter
In one paragraph

Article in American journal of hematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Monoclonal Gammopathy of Thrombotic Significance.American journal of hematology · 2026
    Review
  2. Anti-Platelet Factor 4 Antibody Clonal Heterogeneity and MGUS Status in HIT.medRxiv : the preprint server for health sciences · 2026
    Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Louise ManDepartment of Medicine, University of Virginia, Charlottesville, Virginia, USA.
Adam J KanackDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Emily E MauchDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Noah P SplinterDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Anand PadmanabhanDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.ORCID https://orcid.org/0000-0003-2519-4377

Funding

New approaches to the pathophysiology, diagnosis and management of heparin-induced thrombocytopeniaR01HL158932 · NHLBI · MAYO CLINIC ROCHESTER · PI PADMANABHAN, ANAND · 2021 to 2025
$2.0M
The role of proteoglycans in Heparin-induced thrombocytopenia: Implications for pathophysiology, diagnosis and treatmentK99HL171911 · NHLBI · MAYO CLINIC ROCHESTER · PI KANACK, ADAM J · 2024 to 2025
$332k
NHLBI NIH HHS K99 HL171911NHLBI NIH HHS R01 HL158932NIH HHS HL158932NIH HHS HL171911
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

heparin‐induced thrombocytopeniaHITHIT‐like MGTSMGTS

Identifiers

PMID40944630
PMCPMC12743631

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.