Evidence map›Paper›PMID 40944389›Full record

Observational studyPharmacology research & perspectives2025

Prevalence and Predictors of Opioid Use Before Spine Surgery: A Multicenter, Cross-Sectional Observational Study.

Shania Liu, Jennifer Stevens, Chi Tran, Ashleigh Collins, Jed Duff, Joanna Sutherland, Morgan Oddie, Justine Naylor, Asad Patanwala, Katelyn Jauregui and 1 more

Abstract readObservational StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Pharmacology research & perspectives, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shania LiuFaculty of Medicine and Health, School of Pharmacy, The University of Sydney, Sydney, New South Wales, Australia.
Jennifer StevensSchool of Clinical Medicine, St Vincent's Clinical Campus, University of New South Wales, Sydney, New South Wales, Australia.
Chi TranFaculty of Medicine and Health, School of Pharmacy, The University of Sydney, Sydney, New South Wales, Australia.ORCID 0009-0003-5294-3588
Ashleigh CollinsRoyal Prince Alfred Hospital, Camperdown, New South Wales, Australia.
Jed DuffFaculty of Health, School of Nursing, Centre for Healthcare Transformation, Queensland University of Technology, Brisbane, Queensland, Australia.
Joanna SutherlandRural Clinical School, Coffs Harbour Campus, The University of New South Wales, Sydney, New South Wales, Australia.
Morgan OddieSt George Hospital, Kogarah, New South Wales, Australia.
Justine NaylorWhitlam Orthopaedic Research Centre, Ingham Institute, Liverpool, New South Wales, Australia.
Asad PatanwalaFaculty of Medicine and Health, School of Pharmacy, The University of Sydney, Sydney, New South Wales, Australia.
Katelyn JaureguiFaculty of Medicine and Health, School of Pharmacy, The University of Sydney, Sydney, New South Wales, Australia.
Jonathan PenmFaculty of Medicine and Health, School of Pharmacy, The University of Sydney, Sydney, New South Wales, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spine surgery is performed on 45 000 Australians annually, and opioids are frequently used for pain management before spine surgery, although concerns about their effectiveness and harms persist. Evidence suggests preoperative opioid use is associated with poorer surgical outcomes, yet the prevalence of opioid use before spine surgery in Australia remains unclear. This study aimed to assess the prevalence and predictors of preoperative opioid use among patients undergoing elective spine surgery across geographical settings in NSW, Australia. A multicenter, cross-sectional observational study was conducted with patients scheduled for elective spine surgery at four hospitals representing metropolitan, regional, and rural settings from April 2017 to February 2020. Participants completed a pre-admission questionnaire 2-6 weeks before surgery, providing demographic, clinical, and opioid use data. Preoperative opioid use was reported by 50% (33/66; 95% CI 37%-63%) of participants, with minimal variation across metropolitan (49%), regional metropolitan (54%), and regional hospitals (50%). The most frequently used opioids were oxycodone (32%), codeine (20%), and tapentadol (9%). No significant predictors of opioid use were identified in relation to location, sex, socioeconomic status, smoking, or disability, although trends suggested a higher likelihood of opioid use among patients from lower socioeconomic backgrounds. These findings indicate that 50% of patients use opioids before elective spine surgery, with minimal geographical variation. Given the risks of opioids, efforts to better understand and manage opioid use before spine surgery are warranted. Addressing this issue could lead to more effective pain management strategies and improved patient outcomes.

Indexed as

Analgesics, OpioidPostoperative PainSpineAdultAgedCross-Sectional StudiesElective Surgical ProceduresFemaleHumansMaleMiddle AgedNew South WalesPain ManagementPrevalenceAnalgesics, Opioidopioidspreoperative opioid usespine surgery

Identifiers

PMID40944389
PMCPMC12432400

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.