Evidence map›Paper›PMID 40944329›Full record

SynthesisThe Australasian journal of dermatology2025

Biologic-Induced Paradoxical Psoriatic Alopecia: A Systematic Review.

Yaron Gu, Deshan F Sebaratnam, Mani Makhija, Joshua Farrell

Abstract readSystematic Review
In one paragraph

Synthesis in The Australasian journal of dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yaron GuFaculty of Medicine and Health, The University of New South Wales, Kensington, New South Wales, Australia.ORCID https://orcid.org/0009-0001-1547-8715
Deshan F SebaratnamFaculty of Medicine and Health, The University of New South Wales, Kensington, New South Wales, Australia.ORCID https://orcid.org/0000-0001-5896-8178
Mani MakhijaKossard Dermatopathologists, Macquarie Park, New South Wales, Australia.ORCID https://orcid.org/0000-0001-6200-0055
Joshua FarrellFaculty of Medicine and Health, The University of New South Wales, Kensington, New South Wales, Australia.ORCID https://orcid.org/0000-0001-6531-9360

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A systemic review was completed of primary research articles reporting patient outcomes in paradoxical psoriatic alopecia in association with biologic therapy. Our search strategy identified 96 patients from 45 studies in addition to our own case. Our review indicates a higher prevalence of paradoxical psoriatic alopecia in younger female patients, most commonly secondary to TNF-alpha inhibitors. Unlike alopecia secondary to psoriasis vulgaris, a mixed inflammatory infiltrate featuring lymphocytes, plasma cells and eosinophils was observed. Remission was observed in most patients, including approximately a third of whom continued biologic therapy. Trial Registration: PROSPERO registration number: CRD42023471174.

Indexed as

AlopeciaBiological ProductsPsoriasisFemaleHumansBiological Productsalopeciabiological productspsoriasistumour necrosis factor‐alpha

Identifiers

PMID40944329
PMCPMC12687687

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.