ArticleAnnals of clinical and translational neurology2025
Prevalence of Stroke and Diagnostic Performance of Emergency MRI in Acute Isolated Dizziness.
Article in Annals of clinical and translational neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Dizziness in the emergency department and risk of stroke: A systematic review and meta-analysis.PloS one · 2026Pooled it
- Diagnostic Performance of Mobile Low-Field MRI and CT for Acute Headache as the Isolated Clinical Manifestation in the Neurology Emergency Department.CNS neuroscience & therapeutics · 2026Article
- Diagnostic challenges in posterior circulation ischemic stroke presenting with acute dizziness and vertigo.Frontiers in neurology · 2026Review
- Risk stratification for stroke in acute persistent vertigo: development and internal validation of a multivariable prediction model.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
objectiveStroke is frequently misdiagnosed in patients presenting with acute isolated dizziness; the optimal imaging modality for this population remains debated. This study aimed to determine the prevalence of stroke among patients with isolated dizziness and to assess the diagnostic accuracy of magnetic resonance imaging (MRI) and computed tomography (CT) for stroke detection.
methodsConsecutive patients presenting to the neuroemergency department with acute dizziness between April and December 2024 were enrolled. Isolated dizziness, defined as dizziness or vertigo without accompanying neurological deficits, was identified. Clinical characteristics were compared between patients with and without stroke. The diagnostic performance of MRI and CT for detecting stroke in patients with isolated dizziness was evaluated.
resultsAmong 251 patients with acute dizziness, 129 (51.4%) exhibited isolated dizziness. Of these, 121 (93.7%) underwent emergency MRI. Acute ischemic stroke was diagnosed in 33 out of 129 patients (25.6%) and hemorrhagic stroke in 3 patients (2.3%) with isolated dizziness. Clinical characteristics were similar between patients with and without stroke. The sensitivity and specificity of MRI for detecting acute stroke were 0.939 (95% CI, 0.798-0.993) and 1.000 (95% CI, 0.959-1.000), respectively, whereas CT demonstrated a sensitivity of 0.519 (95% CI, 0.319-0.713) and specificity of 0.795 (95% CI, 0.647-0.902).
interpretationStroke is a frequent but underrecognized cause of isolated dizziness. Clinical features and emergency CT provide limited diagnostic value, whereas MRI offers high accuracy for detecting stroke in this population. Employing MRI as the first-line imaging modality for patients presenting with dizziness may substantially reduce the risk of misdiagnosis.
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