Evidence map›Paper›PMID 40944278›Full record

ReviewNutrients2025

Egg Yolk Immunoglobulins (IgY) Purification, Activity Enhancement, and Potential Benefits for Human Health.

Huilong Qiu, Xiaomin Jin, Xiaomei Zhang, Ke Chen, Lianshun Wang, Jiaqiang Huang

Abstract readReview
In one paragraph

Review in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Huilong QiuDepartment of Nutrition and Health, China Agricultural University, Beijing 100083, China.
Xiaomin JinCollege of Marine Resources & Environment, Hebei Normal University of Science & Technology, Qinhuangdao 066600, China.
Xiaomei ZhangZaozhuang Animal Husbandry and Fishery Development Center, Zaozhuang 277800, China.
Ke ChenDepartment of Nutrition and Health, China Agricultural University, Beijing 100083, China.
Lianshun WangSchool of Fisheries and Life Science, Dalian Ocean University, Dalian 116023, China.
Jiaqiang HuangDepartment of Nutrition and Health, China Agricultural University, Beijing 100083, China.ORCID 0000-0002-6501-3086

Funding

the National Key R&D Program of China 2022YFD2101003
6 · The paper itself

Abstract

With the rapid development of the laying hen industry and the continuous innovation of farming technology, egg production continues to increase. Eggs are rich in proteins, lipids, and immunoglobulins (IgY) found in the egg yolk. IgY can be used to treat human diseases and prevent bacterial and viral infections. In addition, IgY has advantages over IgG in biological structure and function and is characterized by high specificity, safety, yield, and economic efficiency. This review describes the basic structure and properties of IgY, lists a variety of IgY purification methods, and outlines measures to maintain and enhance its activity, focusing on the current status of its research in immunoprevention and treatment of human diseases and outlines its importance, and finally proposes the current challenges and future research priorities of IgY in the field of biomedical research to provide a scientific basis for the wide range of applications of IgY in human health.

Indexed as

Egg YolkImmunoglobulinsAnimalsChickensHumansIgYImmunoglobulinsactivity enhancementegg yolk immunoglobulins (IgY)health benefitspurification

Identifiers

PMID40944278
PMCPMC12430573

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.