Evidence map›Paper›PMID 40944122›Full record

ArticleNutrients2025

Enhanced Cognitive Behavioral Therapy for Young Adolescents with Anorexia Nervosa: Identifying Predictors of Treatment Response.

Simona Calugi, Mirko Chimini, Anna Dalle Grave, Gianmatteo Cattaneo, Maddalena Conti, Riccardo Dalle Grave

Abstract read
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Simona CalugiDepartment of Eating and Weight Disorders, Villa Garda Hospital, Via Monte Baldo, 89, 37016 Garda, VR, Italy.ORCID 0000-0002-4028-1877
Mirko ChiminiDepartment of Eating and Weight Disorders, Villa Garda Hospital, Via Monte Baldo, 89, 37016 Garda, VR, Italy.
Anna Dalle GraveDepartment of Eating and Weight Disorders, Villa Garda Hospital, Via Monte Baldo, 89, 37016 Garda, VR, Italy.
Gianmatteo CattaneoDepartment of Eating and Weight Disorders, Villa Garda Hospital, Via Monte Baldo, 89, 37016 Garda, VR, Italy.ORCID 0009-0004-0607-4606
Maddalena ContiDepartment of Eating and Weight Disorders, Villa Garda Hospital, Via Monte Baldo, 89, 37016 Garda, VR, Italy.
Riccardo Dalle GraveDepartment of Eating and Weight Disorders, Villa Garda Hospital, Via Monte Baldo, 89, 37016 Garda, VR, Italy.ORCID 0000-0002-9796-3721

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: This study aimed to identify baseline demographic, clinical, and psychosocial predictors of treatment response in adolescents with anorexia nervosa (AN) undergoing an intensive 20-week enhanced cognitive behavioral therapy (CBT-E) program, which included inpatient and day patient phases. Treatment outcomes were assessed at the end of intensive treatment (EOIT) and at a 20-week follow-up. (2) Methods: A prospective cohort of 68 adolescents under the age of 16 consecutively admitted to intensive CBT-E was evaluated. Baseline measures included body mass index (BMI)-for-age percentiles, percentage of expected body weight (%EBW), eating disorder psychopathology (EDE-Q), general psychopathology, and functional impairment. (3) Results: Of those who began treatment, 83.4% completed the program and 70.2% were available for follow-up assessment. Based on intent-to-treat analysis, 94.1% achieved a "good BMI outcome" and 73.5% met criteria for "full response" at EOIT. At follow-up, 64.7% maintained a good BMI and 55.9% sustained a full response. Completers' analysis indicated that baseline body weight, clinical impairment, general psychopathology, and weight regain influenced treatment outcomes. However, no baseline demographic or clinical variables predicted treatment completion or outcome at either time point at intention-to-treat analysis, except that younger age at admission was linked to higher eating disorder psychopathology at follow-up. (4) Conclusions: In treatment completers, certain baseline clinical factors and weight regain influenced outcomes, while in the full sample, younger age predicted greater residual psychopathology at follow-up. These findings, if confirmed, emphasize the need for early intervention, focused support for weight regain, and potential adaptations of CBT-E for early adolescents.

Indexed as

Anorexia NervosaCognitive Behavioral TherapyAdolescentBody Mass IndexFemaleHumansMaleProspective StudiesTreatment OutcomeWeight Gainadolescentsanorexia nervosacognitive behavior therapycohort studyfull responseinpatient treatmentpredictorsprospective study

Identifiers

PMID40944122
PMCPMC12430339

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.