Evidence map›Paper›PMID 40944048›Full record

ArticleJournal of clinical medicine2025

The Total Artificial Heart: A Historical Perspective.

Daniele Masarone, Rita Gravino, Luigi Falco, Dario Catapano, Fabio Valente, Cristiano Amarelli, Claudio Marra, Michelle Kittleson, Pierino Di Silverio, Emilio di Lorenzo

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daniele MasaroneDepartment of Cardiology, AORN dei Colli-Monaldi Hospital, 80131 Naples, Italy.ORCID 0000-0002-6781-7424
Rita GravinoDepartment of Cardiology, AORN dei Colli-Monaldi Hospital, 80131 Naples, Italy.
Luigi FalcoDepartment of Cardiology, AORN dei Colli-Monaldi Hospital, 80131 Naples, Italy.ORCID 0009-0005-5669-574X
Dario CatapanoDepartment of Cardiology, AORN dei Colli-Monaldi Hospital, 80131 Naples, Italy.
Fabio ValenteDepartment of Cardiology, AORN dei Colli-Monaldi Hospital, 80131 Naples, Italy.
Cristiano AmarelliDepartment of Cardiac Surgery and Transplant, AORN dei Colli-Monaldi Hospital, 80100 Naples, Italy.ORCID 0000-0002-7949-7771
Claudio MarraDepartment of Cardiac Surgery and Transplant, AORN dei Colli-Monaldi Hospital, 80100 Naples, Italy.
Michelle KittlesonDepartment of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.ORCID 0000-0003-4492-2691
Pierino Di SilverioCampania Region Transplant Center, AORN dei Colli-Monaldi Hospital, 80131 Naples, Italy.
Emilio di LorenzoDepartment of Cardiology, AORN dei Colli-Monaldi Hospital, 80131 Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Scientists, physicians, and engineers have long endeavored to develop a device capable of replacing the function of the heart. The objective is to create a machine or pump for patients suffering from advanced biventricular heart failure, where survival until transplantation is feasible. These total artificial hearts are designed to sustain the patient until a donor heart becomes available. This review aims to present an overview and historical context of the development of the total artificial heart, analyze the currently utilized devices, and briefly discuss future technological innovations in total artificial heart systems.

Indexed as

advanced heart failurehistory of medicinetotal artificial heart

Identifiers

PMID40944048
PMCPMC12428799

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.