ArticleJournal of clinical medicine2025
Comparison of the Effect of CFTR Modulators
Marianna Pócsi, Libor Fila, Csaba Péterfia, Adrien Halász, Tibor G Szanto, Beáta Mészáros, Judit Major, István Laki, Hajnalka Szabó, György Panyi and 4 more
Abstract read
In one paragraphArticle in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
14 authors.
Marianna PócsiDepartment of Laboratory Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.ORCID 0000-0001-6846-5742 Libor FilaDepartment of Pulmonology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, 150 06 Prague, Czech Republic.ORCID 0000-0002-5036-4457 Csaba PéterfiaDepartment of Pediatrics, Faculty of Medicine, University of Pécs, 7624 Pécs, Hungary.ORCID 0009-0001-6198-7959 Adrien HalászNational Korányi Institute for Pulmonology, 1122 Budapest, Hungary.
Tibor G SzantoDepartment of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Beáta MészárosDepartment of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Judit MajorDepartment of Pediatrics, Faculty of Medicine, University of Pécs, 7624 Pécs, Hungary.
István LakiTörökbálint Institute for Pulmonology, 2045 Törökbálint, Hungary.
Hajnalka SzabóDepartment of Pediatrics, Albert Szent-Györgyi Medical School, University of Szeged, 6725 Szeged, Hungary.
György PanyiDepartment of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.ORCID 0000-0001-6227-3301 István BaloghDepartment of Medical Genetics, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.ORCID 0000-0003-3397-2829 Margarida D AmaralBioISI-Biosystems & Integrative Sciences Institute, Faculty of Sciences, University of Lisboa, 1749-016 Lisboa, Portugal.
Milan MacekDepartment of Biology and Medical Genetics, 2nd Faculty of Medicine, Charles University and Motol University Hospital, 150 06 Prague, Czech Republic.ORCID 0000-0002-5173-5280 Béla NagyDepartment of Laboratory Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.ORCID 0000-0002-5700-3267 Funding
National Research, Development, and Innovation Office FK 135327
6 · The paper itselfAbstract
Elevated human epididymis protein 4 (HE4) levels decreased in patients with CF (pwCF) in response to CFTR-specific drugs and negatively correlated with FEV1% predicted values (ppFEV1).
Indexed as
biomarkerCFTR modulatorcystic fibrosisHE4ppFEV1treatment efficacy
Identifiers
PMID40943949
PMCPMC12429638
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