Evidence map›Paper›PMID 40943670›Full record

ArticleInternational journal of molecular sciences2025

Acidic Sophorolipid Biosurfactant Protects Serum Albumin Against Thermal Denaturation.

Julia Ortiz, Paulo Ricardo Franco Marcelino, José A Teruel, Francisco J Aranda, Antonio Ortiz

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julia OrtizDepartamento de Bioquímica y Biología Molecular-A, Facultad de Veterinaria, Universidad de Murcia, 30100 Murcia, Spain.
Paulo Ricardo Franco MarcelinoLaboratório de Bioprocessos e Produtos Sustentáveis (LBios), Escola de Engenharia de Lorena (EEL), Universidade de São Paulo (USP), São Paulo 05508-220, Brazil.ORCID 0000-0002-9792-4810
José A TeruelDepartamento de Bioquímica y Biología Molecular-A, Facultad de Veterinaria, Universidad de Murcia, 30100 Murcia, Spain.ORCID 0000-0003-2256-3368
Francisco J ArandaDepartamento de Bioquímica y Biología Molecular-A, Facultad de Veterinaria, Universidad de Murcia, 30100 Murcia, Spain.
Antonio OrtizDepartamento de Bioquímica y Biología Molecular-A, Facultad de Veterinaria, Universidad de Murcia, 30100 Murcia, Spain.ORCID 0000-0001-9645-9614

Funding

FAPESP - Brazil (São Paulo Research Foundation) Process numbers 2019/19757-0 and 2016/10636-8
6 · The paper itself

Abstract

Sophorolipids (SLs) constitute a group of unique biosurfactants in light of their unique properties, among which their physicochemical characteristics and antimicrobial activity stand out. SLs can exist mainly in acidic and lactonic forms, both of which display inhibitory activity. This study explores the interaction of non-acetylated acidic SL with bovine serum albumin (BSA). SL significantly enhances BSA's thermal stability, increasing its midpoint unfolding temperature from 61.9 °C to approximately 76.0 °C and ΔH from 727 to 1054 kJ mol

Indexed as

Oleic AcidsProtein DenaturationSerum Albumin, BovineSurface-Active AgentsAnimalsBinding SitesCattleHydrophobic and Hydrophilic InteractionsMolecular Docking SimulationProtein BindingSpectroscopy, Fourier Transform InfraredTemperatureOleic AcidsSerum Albumin, BovinesophorolipidSurface-Active AgentsbiosurfactantBovine Serum Albumin (BSA)sophorolipid

Identifiers

PMID40943670
PMCPMC12429398

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.