Evidence map›Paper›PMID 40943640›Full record

ReviewInternational journal of molecular sciences2025

Advancing Gene Therapy for Phenylketonuria: From Precision Editing to Clinical Translation.

Inseon Yu, Jaemin Jeong

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Minicells derived fromApplied and environmental microbiology · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Inseon YuDepartment of Biohealth Convergence, College of Science and Convergence Technology, Seoul Women's University, Seoul 01797, Republic of Korea.ORCID 0000-0001-5610-9986
Jaemin JeongDepartment of Biohealth Convergence, College of Science and Convergence Technology, Seoul Women's University, Seoul 01797, Republic of Korea.ORCID 0000-0001-9758-7917

Funding

National Research Foundation of Korea 2022R1A2C1002884National Research Foundation of Korea RS-2023-00260529Seoul Women's University 2024-0036
6 · The paper itself

Abstract

Phenylketonuria (PKU) is an inherited disorder caused by mutations in the

Indexed as

Gene EditingGenetic TherapyPhenylketonuriasAnimalsCRISPR-Cas SystemsDependovirusGene Transfer TechniquesHumansNanoparticlesPhenylalanine HydroxylaseTranslational Research, BiomedicalPhenylalanine Hydroxylaseadeno-associated virusanimal modelbase editinggene therapyPhenylketonuria (PKU)

Identifiers

PMID40943640
PMCPMC12428815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.