Evidence map›Paper›PMID 40943613›Full record

ArticleInternational journal of molecular sciences2025

Effects of Oligofructose Supplementation on Growth Performance, Antioxidant Capacity, Immunity, and Intestinal Health in Growing Rabbits.

Liwen Qin, Chunlong Xiao, Menglei Shi, Lu He, Yifei Du, Lifan Lin, Zekai Zhang, Yichen Lin, Yue Feng, Qinghua Liu and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Liwen QinDepartment of Animal Science, College of Animal Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Chunlong XiaoDepartment of Animal Science, College of Animal Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Menglei ShiDepartment of Animal Science, College of Animal Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Lu HeDepartment of Animal Science, College of Animal Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Yifei DuDepartment of Animal Science, College of Animal Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Lifan LinDepartment of Animal Science, College of Animal Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Zekai ZhangDepartment of Animal Science, College of Animal Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.ORCID 0009-0006-0060-4666
Yichen LinDepartment of Animal Science, College of Animal Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Yue FengDepartment of Animal Science, College of Animal Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Qinghua LiuDepartment of Animal Science, College of Animal Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Changchuan YeDepartment of Animal Science, College of Animal Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.

Funding

Fujian Province 2022 Local Science and Technology Development Funds 2022L3085National Key Research and Development Program of China 2023YFD1000500National Key Research and Development Program of China 2024YFD1300803
6 · The paper itself

Abstract

This study aims to investigate the effects of dietary supplementation with different concentrations of oligofructose (FOS) on growth performance, antioxidant capacity, immunity, and intestinal microbial composition in growing rabbits. One hundred female Dehua black rabbits (34 d of age) were randomly assigned to four groups (CON, FOS-1, FOS-2, and FOS-3), with twenty-five rabbits in each group. The CON group received only a basal diet, while the FOS-1/FOS-2/FOS-3 group received the diet supplemented with 0.3%/0.6%/0.9% FOS, respectively. The trial period lasted for 72 days. Our results revealed that FOS supplementation could improve the growing performance of rabbits and decrease the feed/gain ratio. FOS significantly enhanced serum antioxidant enzyme (SOD) and total antioxidant capacity (T-AOC) while reducing malondialdehyde (MDA). The levels of plasmic immunoglobulin (IgG, IgA, and IgM) and intestinal immune factors (IL-1α, IL-2, and sIgA) were significantly improved with the FOS supplement. Additionally, FOS can improve intestinal morphology and enhance the activity of intestinal enzymes, including cellulase, lipase, and protease. Furthermore, FOS supplementation influenced the composition of intestinal microflora by increasing the abundance of

Indexed as

AntioxidantsDietary SupplementsIntestinesOligosaccharidesAnimal FeedAnimalsFemaleGastrointestinal MicrobiomeRabbitsAntioxidantsoligofructoseOligosaccharidesantioxidant capacityimmunityintestinal healtholigofructoserabbits

Identifiers

PMID40943613
PMCPMC12429720

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.