Evidence map›Paper›PMID 40943532›Full record

ReviewInternational journal of molecular sciences2025

Micro RNA in Colorectal Cancer-Potential Diagnostic and Prognostic Markers-An Updated Review.

Weronika Pająk, Jakub Kleinrok, Joanna Pec, Karolina Michno, Jan Wojtas, Miłosz Badach, Barbara Teresińska, Jacek Baj

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Expression ofInternational journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Weronika PająkDepartment of Forensic Medicine, Medical University of Lublin, Jaczewskiego 8b, 20-090 Lublin, Poland.ORCID 0009-0009-9616-0458
Jakub KleinrokDepartment of Forensic Medicine, Medical University of Lublin, Jaczewskiego 8b, 20-090 Lublin, Poland.ORCID 0009-0006-3742-5696
Joanna PecDepartment of Correct, Clinical and Imaging Anatomy, Medical University of Lublin, Jaczewskiego 4, 20-090 Lublin, Poland.ORCID 0009-0000-5525-7338
Karolina MichnoFaculty of Medicine, Medical University of Lodz, al. Tadeusza Kosciuszki 4, 90-419 Lodz, Poland.ORCID 0009-0006-1279-9835
Jan WojtasDepartment of Correct, Clinical and Imaging Anatomy, Medical University of Lublin, Jaczewskiego 4, 20-090 Lublin, Poland.ORCID 0000-0003-1393-3689
Miłosz BadachDepartment of Forensic Medicine, Medical University of Lublin, Jaczewskiego 8b, 20-090 Lublin, Poland.ORCID 0009-0002-4318-0403
Barbara TeresińskaDepartment of Correct, Clinical and Imaging Anatomy, Medical University of Lublin, Jaczewskiego 4, 20-090 Lublin, Poland.ORCID 0000-0002-1101-3566
Jacek BajDepartment of Correct, Clinical and Imaging Anatomy, Medical University of Lublin, Jaczewskiego 4, 20-090 Lublin, Poland.ORCID 0000-0002-1372-8987

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is one of the deadliest and most frequently occurring cancers worldwide. Often diagnosed in advanced stages, it requires more challenging treatment. However, emerging studies highlight the possible role of microRNAs (miRNAs) in the screening, diagnosis, and prognosis of CRC. MiRNAs modulate gene expression and can play both roles in tumor suppressors and oncogenes. In CRC, they influence epithelial-mesenchymal transition (EMT), cell proliferation and migration, apoptosis, autophagy, and patients' treatment response. In clinical applications, they can be used as predictive and prognostic biomarkers as well as for matching the most suitable treatments. Despite its growing popularity, there is still much to discover about their potential usage in medicine.

Indexed as

Biomarkers, TumorColorectal NeoplasmsMicroRNAsApoptosisAutophagyEpithelial-Mesenchymal TransitionGene Expression Regulation, NeoplasticHumansPrognosisBiomarkers, TumorMicroRNAscolorectal cancerdiagnostic markersmicroRNAprognostic markers

Identifiers

PMID40943532
PMCPMC12429582

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.