Deletion of the Epidermal Protease

Eleni Zingkou, Marie Reynier, Georgios Pampalakis, Guy Serre, Nathalie Jonca, Georgia Sotiropoulou

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eleni ZingkouDepartment of Pharmacy, School of Health Sciences, University of Patras, Rion, 26504 Patras, Greece.ORCID 0000-0001-5387-0470

Marie ReynierToulouse Institute for Infectious and Inflammatory Diseases (INFINITy), CNRS, Toulouse University, Inserm, 31024 Toulouse, France.

Georgios PampalakisDepartment of Pharmacy, School of Health Sciences, University of Patras, Rion, 26504 Patras, Greece.ORCID 0000-0002-2119-4292

Guy SerreToulouse Institute for Infectious and Inflammatory Diseases (INFINITy), CNRS, Toulouse University, Inserm, 31024 Toulouse, France.

Nathalie JoncaToulouse Institute for Infectious and Inflammatory Diseases (INFINITy), CNRS, Toulouse University, Inserm, 31024 Toulouse, France.ORCID 0000-0003-3602-0102

Georgia SotiropoulouDepartment of Pharmacy, School of Health Sciences, University of Patras, Rion, 26504 Patras, Greece.

Funding

ERANET-E-RARE-3 Τ3ΕΡΑ-00052

6 · The paper itself

Abstract

Congenital ichthyoses, now grouped under the acronym EDD (Epidermal Differentiation Disorders), include nonsyndromic forms (nEDD) that may be caused by loss-of-function mutations in the

Indexed as

EpidermisIchthyosisKallikreinsMembrane ProteinsSerine Peptidase Inhibitor Kazal-Type 5AnimalsDisease Models, AnimalGene DeletionHumansIntercellular Signaling Peptides and ProteinsMiceMice, KnockoutCDSN protein, humanIntercellular Signaling Peptides and ProteinsKallikreinsKLK5 protein, humanKlk5 protein, mouseMembrane ProteinsSerine Peptidase Inhibitor Kazal-Type 5CDSN-nEDD (Peeling skin syndrome type 1)corneodesmosin (CDSN)Epidermal Differentiation Disorders (EDD)epidermal lipidsepidermal proteolysishuman epidermal equivalent (HEE)kallikrein 5 (KLK5)mouse models

Identifiers

PMID40943523

DOI10.3390/ijms26178605

PMCPMC12429418

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.