Evidence map›Paper›PMID 40943466›Full record

ArticleInternational journal of molecular sciences2025

Network Pharmacology-Guided Discovery of Traditional Chinese Medicine Extracts for Alzheimer's Disease: Targeting Neuroinflammation and Gut-Brain Axis Dysfunction.

Ting Zhang, Sunmin Park

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ting ZhangKey Laboratory of Biological Resources and Ecology of Pamirs Plateau in Xinjiang Uygur Autonomous Region, College of Life and Geographic Sciences, Kashi University, Kashi 844000, China.ORCID 0000-0002-5949-3941
Sunmin ParkDepartment of Bioconvergence, Hoseo University, Asan 31499, Republic of Korea.ORCID 0000-0002-6092-8340

Funding

National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT RS-2023-00208567
6 · The paper itself

Abstract

Neuroinflammation plays a central role in the pathogenesis of Alzheimer's disease (AD), with amyloid-β (Aβ) deposition and neurofibrillary tangles driving both central and peripheral inflammatory responses. This study investigated the neuroprotective and anti-inflammatory effects of

Indexed as

Alzheimer DiseaseBrainDrugs, Chinese HerbalMedicine, Chinese TraditionalNetwork PharmacologyNeuroinflammatory DiseasesPlant ExtractsAmyloid beta-PeptidesAnimalsAnti-Inflammatory AgentsCaco-2 CellsHumansMolecular Docking SimulationNeuroprotective AgentsPC12 CellsRatsAmyloid beta-PeptidesAnti-Inflammatory AgentsDrugs, Chinese HerbalNeuroprotective AgentsPlant ExtractsAlzheimer’s diseasegut–brain axisherbal extractneuroinflammationoxidative stress

Identifiers

PMID40943466
PMCPMC12429143

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.