Evidence map›Paper›PMID 40943375›Full record

ReviewInternational journal of molecular sciences2025

DNA Methylation in Rice: Mechanisms, Regulatory Roles, and Beyond.

Ting Li, Wen-Jing Li, Jian-Hong Xu

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ting LiDepartment of Agronomy, College of Agriculture & Biotechnology, Zhejiang University, Hangzhou 310058, China.
Wen-Jing LiDepartment of Agronomy, College of Agriculture & Biotechnology, Zhejiang University, Hangzhou 310058, China.
Jian-Hong XuDepartment of Agronomy, College of Agriculture & Biotechnology, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0002-5620-0410

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a crucial aspect of epigenetic research, DNA methylation is fundamental to genomic stability, gene transcription regulation, and chromatin remodeling. Rice is a staple food source for roughly half of the world's population. Therefore, optimizing rice yield and stress tolerance is vital for global food security. With the continuous advancement of DNA methylation detection technologies, studies have shown that DNA methylation regulates various rice growth and development processes, including root differentiation and grain development, through the dynamic equilibrium of de novo methylation, maintenance methylation, and demethylation. Furthermore, DNA methylation is crucial in the plant's response to environmental stressors like high or low temperature, drought and salinity. The patterns of DNA methylation modifications are also closely linked to rice domestication and heterosis formation. Therefore, a comprehensive investigation of the DNA methylation regulatory network holds significant theoretical value for rice genetic improvement and molecular breeding. This review offers a systematic analysis of the molecular mechanisms and detection technologies of DNA methylation, as well as its regulatory roles in rice growth and development, stress responses, and other biological processes, aiming to provide a theoretical foundation for rice genetic improvement research.

Indexed as

DNA MethylationGene Expression Regulation, DevelopmentalGene Expression Regulation, PlantOryzaDomesticationEpigenesis, GeneticHybrid VigorPlant BreedingDNA methylationgenetic improvementgrowth and developmentricestress response

Identifiers

PMID40943375
PMCPMC12429608

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.