Evidence map›Paper›PMID 40943366›Full record

ReviewInternational journal of molecular sciences2025

Role of Endoscopic Ultrasound (EUS) in the Era of Precision Medicine for Pancreatic Cancer Through Next-Generation Sequencing Technology.

Giulia Peserico, Caterina Stornello, Martina Tessari, Antonio Scapinello, Matteo Curtarello, Mario Gruppo, Ottavia De Simoni, Alberto Fantin

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Giulia PesericoGastroenterology Unit, Veneto Institute of Oncology IOV-IRCCS, 35128 Padova, Italy.
Caterina StornelloGastroenterology Unit, Veneto Institute of Oncology IOV-IRCCS, 35128 Padova, Italy.ORCID 0000-0002-7379-6834
Martina TessariDivision of Gastroenterology, Department of Surgical, Oncological and Gastroenterological Sciences, Azienda Ospedaliera-Università di Padova, 35128 Padova, Italy.
Antonio ScapinelloAnatomy and Histology Unit, Veneto Institute of Oncology IOV-IRCCS, 35128 Padova, Italy.
Matteo CurtarelloImmunology and Molecular Oncology Diagnostics Unit, Veneto Institute of Oncology IOV-IRCCS, 35128 Padova, Italy.ORCID 0000-0003-3133-4807
Mario GruppoSurgical Oncology of Digestive Tract Unit, Veneto Institute of Oncology IOV-IRCCS, 35128 Padova, Italy.ORCID 0000-0001-5525-5762
Ottavia De SimoniSurgical Oncology of Digestive Tract Unit, Veneto Institute of Oncology IOV-IRCCS, 35128 Padova, Italy.ORCID 0000-0001-8788-5590
Alberto FantinGastroenterology Unit, Veneto Institute of Oncology IOV-IRCCS, 35128 Padova, Italy.ORCID 0000-0002-7206-9117

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with a dismal prognosis; this is in part due to its late diagnosis at advanced stages. For many patients, medical treatment is the only practicable therapy. In recent years, the development of new technologies that investigate genomic biomarkers has improved the concept of precision medicine to treat patients with PDAC. Through endoscopic ultrasound-tissue acquisition (EUS-TA), tissue from pancreatic cancers can be collected; thus, it has the potential to advance personalized treatment by allowing the assessment of genomic alterations. In this review, we explore the role of EUS in genomic profiling and its strengths and pitfalls in obtaining samples for next-generation sequencing (NGS).

Indexed as

Carcinoma, Pancreatic DuctalEndosonographyHigh-Throughput Nucleotide SequencingPancreatic NeoplasmsPrecision MedicineBiomarkers, TumorHumansBiomarkers, TumorEUS-FNBgenetic mutationsNGSpancreatic cancertarget therapy

Identifiers

PMID40943366
PMCPMC12428738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.