Evidence map›Paper›PMID 40943359›Full record

ArticleInternational journal of molecular sciences2025

The Neurotropic Activity of Novel Dermorphin Analogs Active at Systemic and Noninvasive Administration.

Vladislav Deigin, Nikolay Korobov, Olga Volpina, Natalia Linkova, Anastasiia Diatlova, Dmitrii Medvedev, Alexander Krasichkov, Victoria Polyakova

Abstract read
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In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vladislav DeiginShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya St., 16/10, 117997 Moscow, Russia.ORCID 0000-0003-1257-8697
Nikolay KorobovDepartment of Pharmacology, Faculty of Fundamental Medicine, Lomonosov Moscow State University, GSP-1, Leninskie Gory, 119991 Moscow, Russia.
Olga VolpinaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya St., 16/10, 117997 Moscow, Russia.ORCID 0000-0003-0740-6110
Natalia LinkovaDepartments of Hospital Surgery, Belgorod National Research University, 308015 Belgorod, Russia.ORCID 0000-0001-5156-5421
Anastasiia DiatlovaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya St., 16/10, 117997 Moscow, Russia.
Dmitrii MedvedevThe Department of Social Rehabilitation and Occupational Therapy of the St. Petersburg Medical and Social Institute, 72A Kondratievsky St., 195271 St. Petersburg, Russia.ORCID 0000-0001-7401-258X
Alexander KrasichkovDepartment of Radio Engineering Systems of Electrotechnical University LETI, 5F Prof. Popova Str., 197022 St. Petersburg, Russia.
Victoria PolyakovaDepartments of Hospital Surgery, Belgorod National Research University, 308015 Belgorod, Russia.ORCID 0000-0001-8682-9909

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The neuropeptide's multifaceted involvement in various components of neural homeostasis impacts pain and behavioral regulation. One of the highly potent neuropeptides is dermorphin, extracted from the skin of the Amazon frog (

Indexed as

Opioid PeptidesAnalgesicsAnalgesics, OpioidAnimalsGuinea PigsMalePainRatsAnalgesicsAnalgesics, OpioiddermorphinOpioid Peptidesanalgetic activitydiketopiperazineintragastric administrationintranasal administrationneurotrophic peptidesopioid activity

Identifiers

PMID40943359
PMCPMC12429696

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.