Evidence map›Paper›PMID 40943297›Full record

ArticleInternational journal of molecular sciences2025

The Prognostic Value of CIP2A and Its Association with CD31, E-Cadherin, and pAMPK in Lung Cancer.

Peng Yu Lee, Ching-Yu Shih, Chiao-Yin Cheng, Hua Ho, Yen-Lin Chen, Chih-Jung Chang

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Peng Yu LeeDepartment of Emergency Medicine, Far Eastern Memorial Hospital, New Taipei 220, Taiwan.
Ching-Yu ShihCenter for Precision Medicine and Genomics, Tri-Service General Hospital, National Defense Medical University, Taipei 114, Taiwan.
Chiao-Yin ChengDepartment of Emergency Medicine, Far Eastern Memorial Hospital, New Taipei 220, Taiwan.ORCID 0000-0002-0693-7203
Hua HoDepartment of Emergency Medicine, Far Eastern Memorial Hospital, New Taipei 220, Taiwan.
Yen-Lin ChenDepartment of Pathology, Center for Precision Medicine and Genomics, Tri-Service General Hospital, National Defense Medical University, Taipei 114, Taiwan.ORCID 0000-0002-6381-4269
Chih-Jung ChangDepartment of Emergency Medicine, Far Eastern Memorial Hospital, New Taipei 220, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancerous inhibitor of protein phosphatase 2A (CIP2A) is an oncoprotein promoting tumor progression via multiple pathways. Its prognostic significance in lung cancer remains unclear. We analyzed tumor samples from 53 patients with lung cancer undergoing curative surgical resection without prior chemotherapy or radiotherapy. Immunohistochemical staining and H-score quantification were performed to assess CIP2A and related protein expression. Patients were stratified based on CIP2A expression (cutoff value = 218.33). Kaplan-Meier survival analysis produced curves and log-rank tests. Correlations with clinicopathological and molecular markers were assessed. High CIP2A expression was significantly associated with poorer survival (log-rank,

Indexed as

AMP-Activated Protein KinasesAntigens, CDAutoantigensCadherinsIntracellular Signaling Peptides and ProteinsLung NeoplasmsMembrane ProteinsAdultAgedBiomarkers, TumorFemaleHumansKaplan-Meier EstimateMaleMiddle AgedPrognosisAMP-Activated Protein KinasesAntigens, CDAutoantigensBiomarkers, TumorCadherinsCDH1 protein, humanCIP2A protein, humanIntracellular Signaling Peptides and ProteinsMembrane ProteinsAKTAMPKCD31CIP2Alung cancer

Identifiers

PMID40943297
PMCPMC12428206

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.