ArticleInternational journal of molecular sciences2025
Epigallocatechin-3-Gallate Enhances Antioxidant Activity and Improves Testicular and Epididymal Histology in Cadmium-Exposed Prepubertal Rats.
Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Reactive Oxygen and Nitrogen Species in Male Reproductive Health: From Molecular Mechanisms to Clinical Consequences.Antioxidants (Basel, Switzerland) · 2026Review
- Article
- Impact of Cadmium Toxicity on Testicular Function: Risk of Male Infertility.Life (Basel, Switzerland) · 2026Review
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
The prepubertal period represents a critical stage of development, where the reproductive system is susceptible to toxicants such as cadmium (Cd). Cd induces oxidative stress, causes alterations in the antioxidant enzymes and testosterone concentration, and affects reproductive organs. (-)-Epigallocatechin-3-gallate (EGCG), a polyphenol with antioxidant properties, has been studied for its protective effects. We evaluated the effects of EGCG on antioxidant activity and improvement of testicular and epididymal histology in Cd-exposed prepubertal rats. Twenty-eight male Wistar rats, on postnatal day (PND) 21, were distributed into four groups: Ctrl (saline), Cd (1 mg/kg CdCl
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