Evidence map›Paper›PMID 40943165›Full record

ArticleInternational journal of molecular sciences2025

Metagenomic Analysis Reveals the Anti-Inflammatory Properties of Mare Milk.

Ran Wang, Wanlu Ren, Shibo Liu, Zexu Li, Luling Li, Shikun Ma, Xinkui Yao, Jun Meng, Yaqi Zeng, Jianwen Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ran WangCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Wanlu RenCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Shibo LiuCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Zexu LiCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Luling LiCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Shikun MaCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Xinkui YaoCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Jun MengCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Yaqi ZengCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.ORCID 0009-0000-1881-1221
Jianwen WangCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.ORCID 0000-0001-7148-4557

Funding

Xinjiang Uygur Autonomous Region Major Science and Technology Special Project and the Central Guidance for Local Science and Technology Development Fund 2022A02007-1 and ZYYD2025JD02.
6 · The paper itself

Abstract

This study aimed to assess the anti-inflammatory properties of mare milk by analyzing immune markers in mice following gavage of mare milk. Metagenomic sequencing was employed to examine variations in the composition and functional profiles of the intestinal microbiota across different experimental groups. Bacterial diversity, abundance, and functional annotations of gut microbiota were evaluated for each group. The results show that, compared to the control group, the mare milk group exhibited a significant decrease in the pro-inflammatory cytokine IL-6 levels and a significant increase in secretory immunoglobulin A (SIgA) levels (

Indexed as

Anti-Inflammatory AgentsGastrointestinal MicrobiomeMetagenomicsMilkAnimalsCytokinesFemaleHorsesMiceAnti-Inflammatory AgentsCytokinesanti-inflammatory propertieskoumissmare milkmetagenomics

Identifiers

PMID40943165
PMCPMC12428327

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.