Evidence map›Paper›PMID 40943144›Full record

ArticleInternational journal of molecular sciences2025

Profiling of Breast Cancer Stem Cell Types/States Shows the Role of CD44

Hazem Ghebeh, Jumanah Y Mirza, Taher Al-Tweigeri, Monther Al-Alwan, Asma Tulbah

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hazem GhebehCell Therapy and Immunobiology Department, King Faisal Specialist Hospital & Research Centre, P.O. Box 3354, Riyadh 11211, Saudi Arabia.ORCID 0000-0002-3297-3996
Jumanah Y MirzaCell Therapy and Immunobiology Department, King Faisal Specialist Hospital & Research Centre, P.O. Box 3354, Riyadh 11211, Saudi Arabia.
Taher Al-TweigeriOncology Centre, King Faisal Specialist Hospital & Research Centre, Riyadh 11211, Saudi Arabia.ORCID 0000-0002-6652-4419
Monther Al-AlwanCell Therapy and Immunobiology Department, King Faisal Specialist Hospital & Research Centre, P.O. Box 3354, Riyadh 11211, Saudi Arabia.ORCID 0000-0003-2150-5297
Asma TulbahDepartment of Pathology, King Faisal Specialist Hospital & Research Centre, Riyadh 11211, Saudi Arabia.

Funding

King Faisal Specialist Hospital & Research Centre 2190002
6 · The paper itself

Abstract

Multiple markers exist for breast cancer stem cells (CSCs), which are believed to represent the phenotypes of various CSC types and/or states. The relationship between each CSC subpopulation/state and the primary hallmarks of cancer has not been sufficiently clarified. In this study, six CSC markers (CD44

Indexed as

Biomarkers, TumorBreast NeoplasmsCD24 AntigenHyaluronan ReceptorsNeoplastic Stem CellsAdultAgedAldehyde Dehydrogenase 1 FamilyEpithelial-Mesenchymal TransitionFemaleHumansIsoenzymesMiddle AgedNeoadjuvant TherapyPrognosisRetinal DehydrogenaseAldehyde Dehydrogenase 1 FamilyALDH1A1 protein, humanBiomarkers, TumorCD24 AntigenCD24 protein, humanCD44 protein, humanHyaluronan ReceptorsIsoenzymesRetinal DehydrogenaseALDH1BMI1cancer stem cellsCD10CD24CD44hi/CD24loEp-CAMPD-L1

Identifiers

PMID40943144
PMCPMC12428598

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.