Evidence map›Paper›PMID 40943133›Full record

ReviewInternational journal of molecular sciences2025

Linezolid in the Focus of Antimicrobial Resistance of

Slavil Peykov, Boris Kirov, Tanya Strateva

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Synergistic activity of fosfomycin combined with old and new oxazolidinones (linezolid, contezolid, delpazolid, and sutezolid) against bloodstream isolates of vancomycin-resistant Enterococcus faecium.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  5. Article
  6. Article
  7. Identification of the Phenicol Efflux GeneInternational journal of microbiology · 2026
    Article
  8. Article
  9. Harnessing phages to tackle antimicrobial resistance: a Saudi Arabian perspective.Frontiers in cellular and infection microbiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Slavil PeykovDepartment of Genetics, Faculty of Biology, University of Sofia "St. Kliment Ohridski", 8 Dragan Tzankov Blvd., 1164 Sofia, Bulgaria.ORCID 0000-0001-9431-9511
Boris KirovBioInfoTech Laboratory, Sofia Tech Park, 111 Tsarigradsko Shose Blvd., 1784 Sofia, Bulgaria.ORCID 0009-0005-6477-1749
Tanya StratevaDepartment of Medical Microbiology "Corr. Mem. Prof. Ivan Mitov, MD, DMSc", Faculty of Medicine, Medical University of Sofia, 2 Zdrave Str., 1431 Sofia, Bulgaria.ORCID 0000-0002-5197-1849

Funding

European Union-Next Generation EU, through the National Recovery and Resilience Plan of the Republic of Bulgaria project № BG-RRP-2.004-0005 "Improving the research capacity and quality to achieve interna-tional recognition and resilience of the Technical University - Sofia" (IDEAS)
6 · The paper itself

Abstract

Linezolid (LNZ) is a synthetic oxazolidinone antibiotic that inhibits bacterial protein synthesis through binding to ribosomal RNA, also preventing the assembly of the initiation complex during translation. It is one of the last-line therapeutic options for serious infections caused by problematic Gram-positive pathogens, including vancomycin-resistant and multidrug-resistant

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialEnterococcusGram-Positive Bacterial InfectionsLinezolidGenome, BacterialGenomicsHumansMicrobial Sensitivity TestsRNA, Ribosomal, 23SAnti-Bacterial AgentsLinezolidRNA, Ribosomal, 23ScfrEnterococcus faecalisEnterococcus faeciumG2576T mutationlinezolidlinezolid resistance mechanismsoptrApoxtAwhole-genome sequencing

Identifiers

PMID40943133
PMCPMC12428224

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.