ArticleMaterials (Basel, Switzerland)2025
Enhancing Cellular Interactions Through Bioactivation and Local Nanomechanical Reinforcement in Nanodiamond-Loaded 3D-Printed Gellan Gum Scaffolds.
Carmen-Valentina Nicolae, Masoumeh Jahani Kadousaraei, Elena Olăreț, Andrada Serafim, Mehmet Serhat Aydin, Ioana-Teodora Bogdan, Adriana Elena Bratu, Raluca-Elena Ginghină, Alexandra Dobranici, Sorina Dinescu and 2 more
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In one paragraphArticle in Materials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
12 authors.
Carmen-Valentina NicolaeAdvanced Polymer Materials Group, Faculty of Chemical Engineering and Biotechnologies, National University of Science and Technology Politehnica Bucharest, 011061 Bucharest, Romania.ORCID 0000-0003-2729-411X Masoumeh Jahani KadousaraeiCenter of Translational Oral Research, Department of Clinical Dentistry, University of Bergen, 5009 Bergen, Norway.ORCID 0009-0009-6428-9804 Elena OlărețAdvanced Polymer Materials Group, Faculty of Chemical Engineering and Biotechnologies, National University of Science and Technology Politehnica Bucharest, 011061 Bucharest, Romania.ORCID 0000-0001-9593-6140 Andrada SerafimAdvanced Polymer Materials Group, Faculty of Chemical Engineering and Biotechnologies, National University of Science and Technology Politehnica Bucharest, 011061 Bucharest, Romania.
Mehmet Serhat AydinCenter of Translational Oral Research, Department of Clinical Dentistry, University of Bergen, 5009 Bergen, Norway.ORCID 0000-0003-3061-1753 Ioana-Teodora BogdanFaculty of Medical Engineering, National University of Science and Technology Politehnica Bucharest, 011061 Bucharest, Romania.
Adriana Elena BratuAdvanced Polymer Materials Group, Faculty of Chemical Engineering and Biotechnologies, National University of Science and Technology Politehnica Bucharest, 011061 Bucharest, Romania.
Raluca-Elena GinghinăResearch and Innovation Center for CBRN Defense and Ecology, 041327 Bucharest, Romania.ORCID 0000-0003-1908-0234 Alexandra DobraniciDepartment of Biochemistry and Molecular Biology, Faculty of Biology, University of Bucharest, 050095 Bucharest, Romania.
Sorina DinescuDepartment of Biochemistry and Molecular Biology, Faculty of Biology, University of Bucharest, 050095 Bucharest, Romania.ORCID 0000-0001-7196-1712 Kamal MustafaCenter of Translational Oral Research, Department of Clinical Dentistry, University of Bergen, 5009 Bergen, Norway.ORCID 0000-0002-2968-2856 Izabela-Cristina StancuAdvanced Polymer Materials Group, Faculty of Chemical Engineering and Biotechnologies, National University of Science and Technology Politehnica Bucharest, 011061 Bucharest, Romania.ORCID 0000-0003-0685-3947 Funding
Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii PN-IV-P7-7.1-PED-2024-2663, no. PED44/2025
6 · The paper itselfAbstract
The integration of nanomaterials within hydrogel scaffolds offers significant promise in bone tissue engineering by improving mechanical performance and modulating cellular responses through mechanotransductive and biochemical signaling. Previous studies have demonstrated that nanodiamonds (NDs) incorporated in electrospun microfibrillar meshes enhance cellular adhesion, spreading, and cytoskeletal organization through localized mechanical reinforcement. However, the effects of ND loading into soft, bioinert three-dimensional hydrogel matrices remain underexplored. Here, we developed nanostructured 3D printing inks composed of gellan gum (GG) supplemented with a low content of ND nanoadditive (0-3%
Indexed as
3D printingbioactivationgellan gumicariinnanodiamond nanoparticles
Identifiers
PMID40942557
PMCPMC12430653
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