ArticleMaterials (Basel, Switzerland)2025
Polymeric Membrane Electrodes for a Fast End Cost-Effective Potentiometric Determination of Octenidine Dihydrochloride in Pharmaceutical Samples.
Article in Materials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Determining the active substance content in the tested product is an essential part of research for overall assessment of the quality of a medicinal substance. This role can be successfully performed by membrane electrodes that are selective for a specific drug. The novelty of the presented research is the development of the first ion-selective electrode with a polymer membrane phase with the octenidine (OCT) function. Classical ion-selective electrodes (ISE), polymer electrodes with an internal Ag/AgCl electrode, and electrode bodies with glassy carbon were used for the research. The membranes were prepared based on cation exchangers from the borate group and neutral cyclodextrin. All sensors have good parameters, e.g., the polymer electrode with KtpClPB is characterised by a wide linear range of -logc 6-3, a low limit of detection 5 × 10
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