Evidence map›Paper›PMID 40942296›Full record

ArticlePolymers2025

Bioengineered Chitosan-Collagen-Honey Sponges: Physicochemical, Antibacterial, and In Vitro Healing Properties for Enhanced Wound Healing and Infection Control.

David Servín de la Mora-López, Leticia Olivera-Castillo, Jaime López-Cervantes, Dalia I Sánchez-Machado, Jesús Fernando Ayala-Zavala, Herlinda Soto-Valdez, Tomás J Madera-Santana

Abstract read
In one paragraph

Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David Servín de la Mora-LópezCoordinación de Tecnología de Alimentos de Origen Vegetal, Centro de Investigación en Alimentación y Desarrollo, A.C. Carretera Gustavo Enrique Astiazarán Rosas No. 46. Colonia La Victoria, Hermosillo 83304, Sonora, Mexico.ORCID 0000-0003-4131-2556
Leticia Olivera-CastilloDepartamento Recursos del Mar, Centro de Investigación y de Estudios Avanzados del IPN-Unidad Mérida, Carr. Ant. a Progreso Km. 6, Mérida 97310, Yucatán, Mexico.
Jaime López-CervantesDepartamento de Biotecnología y Ciencia de los Alimentos, Instituto Tecnológico de Sonora, Calle Chihuahua, Centro, Urb, No. 1. Colonia Centro, Ciudad Obregón 85000, Sonora, Mexico.ORCID 0000-0001-9847-0067
Dalia I Sánchez-MachadoDepartamento de Biotecnología y Ciencia de los Alimentos, Instituto Tecnológico de Sonora, Calle Chihuahua, Centro, Urb, No. 1. Colonia Centro, Ciudad Obregón 85000, Sonora, Mexico.
Jesús Fernando Ayala-ZavalaCoordinación de Tecnología de Alimentos de Origen Vegetal, Centro de Investigación en Alimentación y Desarrollo, A.C. Carretera Gustavo Enrique Astiazarán Rosas No. 46. Colonia La Victoria, Hermosillo 83304, Sonora, Mexico.ORCID 0000-0002-0691-6453
Herlinda Soto-ValdezCoordinación de Tecnología de Alimentos de Origen Vegetal, Centro de Investigación en Alimentación y Desarrollo, A.C. Carretera Gustavo Enrique Astiazarán Rosas No. 46. Colonia La Victoria, Hermosillo 83304, Sonora, Mexico.ORCID 0000-0001-6654-8376
Tomás J Madera-SantanaCoordinación de Tecnología de Alimentos de Origen Vegetal, Centro de Investigación en Alimentación y Desarrollo, A.C. Carretera Gustavo Enrique Astiazarán Rosas No. 46. Colonia La Victoria, Hermosillo 83304, Sonora, Mexico.ORCID 0000-0003-3844-2800

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial-mediated infections represent a major risk factor for chronic wounds. Numerous polymeric dressings have been proposed to reduce this incidence and promote wound healing. In the present investigation, chitosan/collagen/honey-based sponges were prepared by freeze-drying. The effect of honey incorporation at different concentrations on the physicochemical and antibacterial properties of the sponges was evaluated. The SEM images showed that the surface and cross-sections of all samples had a porous structure. The pore size gradually increased in the range of 78.14 to 126.9 μm due to the increase in honey content in the sponges. This property resulted in considerably higher porosity degrees (79.90-90.13%) and absorption rates (ranges of 1357-1665% in deionized water and 865-1938% in PBS solution) in honey-loaded systems. Conversely, the honey composite formulations exhibited a reduction in permeability, with WVTR values ranging from 131.01 to 99.39 gh

Indexed as

bacterial infectionchitosanchronic ulcerscollagenhoneysponge dressings

Identifiers

PMID40942296
PMCPMC12431070

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.